Hello, and welcome to the
hundredth episode of Shaping Fire. I am your host Chango Lowes. Before
we get to the meat of the program, I'm gonna take a little bit of time here
at the top of the show and share some of the philosophy and themes behind the
Shaping Fire podcast that we've never really talked about in the
first a hundred episodes. I get questions about these things and
I figure I might as well, you know, what better time than a hundred episode
to share it with you. So number one is, uh, of course the main guide behind the
program is to make cannabis enthusiasts self-sufficient. Uh, I appreciate that access is increasing
across the United States as normalization kind of creeps in and, and it's good
to support those stores. However, um, I also think that patients should be able
to grow and produce their own medicine and preparations at home. And every episode of Shaping
Fire works towards that goal. Also, each episode I try to make sure is
packed with information that you can take action on. I try to include everything you need in
an episode to make a decision or take action, or at least feel like
you have a handle on that topic. Too often I listen to a podcast to learn, and I'm only given about 65 or
70% of the information I actually need. And so I still have to continue
my research to fill in the holes With Shaping Fire episodes, I really try to give you everything
you need to start making decisions. And sure, there's almost always
more research that's needed, but at least you know that you have the
basics covered and you can go forward on your second layer. Race
Research with Confidence. Um, I book Shaping Fire
episodes or my guests based on topics, and I don't do company profiles
and I don't do people profiles. Um, I find a topic that I'm interested
and I think that the audience would be interested in, and that is
undercover in cannabis media. After I've got that topic and
that I want what I want to cover, I then go and find a guest who is
an industry expert in that area, and then I invite them on the show. Um, every week I get lots of people
interested in being on the show, or they're press agents and, and they let me know that this
person is very interesting, except Shaping Fire is
not about that person. Shaping fire is about cannabis patients, and those are the people
who are important. And so I see my role as a role of service, bringing you topics that you
are interested in learning in, and then we just go and find
the right person for it. Before people are on my
show, we have a conversation. So they too understand that this show is
not about them, and it's not about me. Is this doing this show is a role
of service for cannabis patients, and that's how we treat it. And people who don't work in that way, they don't end up on shaping fire. So
that's how I choose guests. Similarly, I choose my advertisers based
on those same kinds of morals. I choose advertisers that have a message
or a product that I actually think that regenerative minded Cannabis
u are going to be interested in. And so because of that,
you don't see me, uh, accepting money from a
bottled salt fertilizer companies. And boy, do they
wanna be on the show. And gosh, have I had to turn down a lot of money, but it would be very difficult for
me to have all of these regenerative guests and then cut to, and commercial that is
some kind of a plus B salt nutrient for indoor. It just
would be out of integrity for me. And so I don't do it, um, online. I don't fight with trolls. I just
restrict them and move on with my life. You know, a lot of people really get
into the fight online, and I just don't, I just don't have the energy for it. I don't like that feeling of stress
in the middle of my chess when, when people are involved in
online fighting. So, so I just, I just don't even respond and I
block 'em or restrict them and get on with my life. I got way more
important things to do than, than internet fighting. My first podcasts, my first 55 of them were actually
for entrepreneur.com. Um, I worked with them for a
year doing weekly shows, and I recommend that you go over
to Go entrepreneur.com and, uh, check those out. Um, I love the
guys there. Um, but, you know, I realized that I was pretty darn
good at this podcasting thing, and I wanted to own all my own
intellectual property. So, um, I said goodbye to the fellas
and I wished them best, and we're all still friends. And, uh, and I formed Shaping Fire so that I
could be in control of my own destiny, choose my own advertisers, own my own
intellectual property, and move forward. And now, five years in, I think
that was a great decision. And, uh, happily I've been met with a lot of
success and can support myself, um, off the show. Uh, I've also done a hundred episodes of
Shaping Fire over the last five years, uh, 20 per year, roughly twice a month
with, uh, a break around Christmas. So at 20 episodes a year. Um,
it's certainly not as, uh, fast as many podcasts that have got
weekly or even daily episodes. Uh, I've just never been
interested in that and I, I spend too much time curating
my content and, and finding, um, difficult to find guests and then
reading their books before they're on the show, or if they're a scientist, all
of their scientific papers. And, um, doing lots of episodes has just never
been attractive to me, attractive to me. I'd rather do less shows and have
them be more in depth. And that's, that isn't to to shame
anybody else's show. Like, there's lots of room in this
scene for lots of different shows, and people love different types
of entertainment and education. So while Shaping Fire isn't the show
that I'm gonna be smoking out with the guest and we're gonna be talking
about what we're smoking on, um, there's certainly a place for that. And I think that there's enough room
for everybody. And certainly, um, my audience appreciates
how, how I approach things. There's also the YouTube channel, in
case you're not familiar with that, there's almost 200 videos of, um, various speakers speaking on
cannabis and antigens. Um, and it's, it's kind of funny because the, the, the YouTube channel was an
accident actually. Um, when
I started traveling, um, back in 2015 or so, uh, people were flying me out to
speak at cannabis conventions. Um, you know, since I was at
the Cannabis convention, I was also going to see
really good speakers, and it, it seemed like a waste to not record them. So every time I went to see a speaker, I also recorded the speaker so
that I could bring home that content to you so you could enjoy
it without ever having to travel. And so I started dumping those
videos onto the YouTube channel, and, you know, eventually more and more people started
watching them and subscribing. And, you know, we've got over
10,000 subscribers now. I think we're at like 13,000
perhaps, and, you know, over, over a million and a half
minutes served and, you know, serving 30 to 40,000 people a
month. So, um, it's pretty good. It doesn't generate any money at all. Um, but it's just a good
resource for people. And, and I'm glad we started
it all that time ago. I talk in this episode a
lot about patients I've been
involved with, and I have, but I don't practice medicine. I'm not
a doctor. Um, or do I have an office? Nor do I charge a fee
for these consultations. So you'll hear me refer to
patients a lot in this episode. And this is simply because
when you are interviewing medical doctors and scientists every week and then speaking about that publicly, you start to attract people
with questions and stories. And then I tend to keep
in contact with people. And so it's been over this decade
of learning from patients that I have been able to amass this knowledge
for myself as a cannabis patient and to help the people around me here
on Vaon Island where I live. But, but it's important to be sure that, that I am not a doctor and, uh, I am not cosplaying as a doctor
at all, nor charging money. So not practicing medicine
without a license. And I always encourage you to talk to
your doctors about anything that you decide to do after listening
to Shaping Fire. That said, with this episode, I'm trying to offer this
dosing information in a way so people don't have to reach out to
me all the time. So, um, please, this is not an invitation to send me
Instagram messages and emails asking me about, um, your specific,
um, ailment. Um, I'm, I'm not really working with patients
anymore except for my local neighbors. So, so I hope that you get what
you need from this episode, and I tried to make it as complete
as possible just for that reason. So going forward, you can
expect more soil episodes, more regenerative techniques, more
making hash and oil and such at home, and of course, more cannabis and health. And I'm going to keep up
with the mushrooms, dmt, and
other antigen topics too. So thank you for being part of the Shaping
Fire community and thanks for telling your friends about shaping fire. If you wanna learn about cannabis health
cultivation and technique efficiently and with good cheer, I encourage
you to subscribe to our newsletter. We'll send you new podcast
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the newsletter and be entered into this month's and all future
newsletter prize drawings. You are listening to Shaping Fire,
and I am your host, Chango LOEs. My guest today is, well, me sh go Los. I have been a cannabis educator for the
last decade and have been involved with cannabis medicine since 1989. I have listened to the stories of
more patients than I can count. I founded the VAs on Island Marijuana
Enthusiast Alliance many years ago to gather cannabis patients and those who
love them to share best practices and to bring in international guest speakers.
And boy oh boy, has that been a success. I presently spend my time producing the
Shaping Fire Podcast as I recover from burnout and study neuro
divergence. This is a long episode, but I was careful to add out
anything that felt like filler. My hope is that it's a comprehensive
guide for those who are new to dosing cannabinoids so they can take their next
steps toward healing with confidence. This is the first time I've
ever recorded solo like this, so perhaps cut me some slack. If
you like this sort of episode, please let me know because I have an
episode like this written on the 90 Day Cancer Protocol too that I do if you
happen to like this format. Okay, friends, let's go. So here we are friends. I have been wanting to record this
episode for a couple years now. It's one of the most common
things that I'm asked for. I I teach about dosing
a lot to, uh, you know, small groups of people in
their homes. And, uh, you know, occasionally I'm asked to do this talk
at, um, you know, at conventions or, or, or, you know, caregiver
events or whatever. Um, but those are always so informal and
there's always lots of questions. It, it never really, um, seemed appropriate
to, to put any of those recordings out. So for the first time here
for the hundredth episode,
I figured I would, uh, uh, give it a shot to, um, uh, put this
body of information that I've got, um, here for you, um, so that
you can, um, you know, potentially learn some yourself and
share it with caregivers and family and friends in a way that can get folks
up to speed on cannabis dosing in a way that, um, is useful to them in their
everyday life and isn't packed with misinformation. Cuz as we all know, most
of the information that you can get, um, from just searching
online is pretty bad. Um, but I will take a moment
and plug project c.org. Um, Martin Lee has done a great job
pulling together, um, you know, accurate cannabis information with, um,
excellent articles on different, um, medical conditions and using
cannabis for it. And, um, at the end of all the articles, um, they have got links to all of the
original cannabis white papers, um, on that particular cannabis
medical topic. So, um, if I would recommend that you go anywhere
else, it would be to, uh, project cbd. So this episode is primarily
designed for patients and those who love them. Um, you know, I pretty much consider everyone who
uses cannabis to be a, you know, air quotes cannabis
patient because, you know, even if you're just using
cannabis as a, you know, you know, recreationally cuz it, you know, makes you feel good and maybe
decreases your anxiety and, you know, causes you to have fun when you're out
in nature or playing video games or whatever, you're using
it, uh, to, you know, as a euphoric to improve your
life so that, um, you know, you have a life
that's worth living, right? Things are hard now for a lot of people, and a lot of us turn to cannabis for
quality of life and, um, you know, and that's a good thing. Um, so I wanna point out that the
vocabulary I'll be using today is a layman's vocabulary, primarily. Um, it's true that I do a lot of teaching
to caregivers and doctors and nurses and things like that to help them
understand how best to, you know, assess and plan for and dose
cannabis medicine in their clinics. But the vast majority of the people that
I talk to are just like regular folks, you know, like somebody's mom, somebody's
uncle, somebody's neighbor, um, and, and hell, a lot of the times it's just the people
that I run into at the grocery store on the island where I live. And so, um,
that's, those are the people that, uh, you know, i, I talk to most because
I think that's where I can have, um, the most authentic, uh, impact. So, um,
this episode is, is for those folks, for you folks, um, who are don't, don't
necessarily have medical training, and yet you really want to have a
specific dosing information, um, for yourself or to help the people
that you like. So, um, you know, my experience is with,
um, consulting, teaching, however you wanna put it, for
over a thousand patients, um, for almost a decade
now. And also as a, um, a medicine maker for myself. I've had
a brain injury, a couple car accidents, things like that. And so, um,
I've had the opportunity to, uh, participate in the Washington
medical market, um, and, and learn lots of different feedback
from different types of patients at different ages and, uh, you know, economic levels on
different types of products, from tinture to flour to
edibles to, uh, you know, um, what we call rso. But, uh,
I don't prefer that name. I I prefer just full extract cannabis,
oil, all that stuff, you know, and, and, and after you spend this much time talking
with people and learning everybody's best practices and then giving suggestions
to people and then hearing back from them, you know, I've
developed a pretty, um, good, uh, body of information in my head. And
then, um, you know, four years ago, um, uh, I put together a study
on vaon on CBD oil dosing, I guess has five years ago. No. Um, and then three years ago I did
the same thing with, uh, CBG Oil, and that brought up a whole bunch of, uh, very interesting applications for cbg and
we'll talk about that later. And then, um, I'm just setting up one right now
on C B D V, the Veron version of, uh, cannabidiol. And so, um, you know, these are opportunities that
really afford me a lot more, um, first person information than, than
even most clinical doctors. So, so here we go. During the first set, we're gonna talk about some basics
about the endocannabinoid system and, uh, different methods of use of cannabis
and their pros and cons specifically for patients. And then, uh, during the
second set, we're gonna talk about, um, the specific, uh, cannabinoids
that we are most familiar with, and we, and we have actual dosing
information for. And then, um, to help get your head wrapped around, um, like how to actually apply this
stuff. The third set is, uh, is all about very specific
medical conditions, um, that once we talk about those medical conditions and how to think
through the dosing on those, you'll have a really good idea of
how to think through similar medical conditions and, and how to
think through dosing on those. Because my goal with this
episode is not just like, give you a spreadsheet in your head of,
okay, if you've got this, take this, if you've got this, take this. Because
really every human is different. And in individualized
medicine is something that
we can attain with cannabis. So, so let's do that. And so instead
of just giving you very, um, you know, tight dosing specifications for, for assuming everybody's the same, I want to teach you how to think about
cannabis dosing so you can understand why the dosing is the way it is. And, and so you can make subtle changes
based on you or your patient's needs, and you can be a mo more
dynamic cannabis user than, um, than you would be if you were
just, you know, hearing, you know, the specific milligrams
you need. Because honestly, people's dosing needs flexibility. Let's start by talking about
the endocannabinoid system. The endocannabinoid system is,
uh, the human body's primary, uh, regulatory system. It's kind of like a thermostat for all
of the mission critical systems of the body. Um, if you've got a system
that's running hot, it cools it down. And if you've got a bodily
system that's sluggish, um, it fires it up and, um, it brings everything back to
the middle, A balanced place, what they call in, um, Chinese
medicine to tonify, right, to bring back into balance. And that's
what the endocannabinoid system does. Um, I think of it, and, and I often explain
it as being a second grade teacher. When the second grade
teacher is in the classroom, the kids are generally behaving, right? They're doing their work
and doing their thing. Um, but if somebody comes to the door and the
second grade teacher needs to step out into the hallway for a moment,
the kids will be fine for a while, but eventually some kid will, you know, crack up or make a noise and then another
kid will crack up and then, you know, eventually a bunch of the kids are
cracking up until the second grade teacher comes back into the room. Same thing
with your endocannabinoid system. When the endocannabinoid system
is thriving and strong, um, it is regulating all of those bodily
systems the way that it's supposed to. Um, the challenge comes into when, um,
our endocannabinoid system, um, becomes weakened and different
folks have different systems fall into dysregulation. Um, that's
one of the odd things of why, uh, endocannabinoid deficiency can look
so different because when you have a weakened endocannabinoid system, you know, different people have got different
second grade students that go bad, right? So some, somebody, somebody
might, um, see it in, uh, migraines and somebody else might get
it in irritable bowel syndrome and somebody else might get
fibromyalgia. And, um, since somebody else might get
a combination of these things, and the longer they ignore it, they start to stack up more and
more of these ailments from the endocannabinoid system no longer
effectively keeping their different bodily systems in balance. And so that's why it's so important to
keep the endocannabinoid system from, um, beginning becoming deficient. Some of the most common first things we
see are ibs, fibromyalgia, migraines, but also autoimmune issues and
Parkinson's and dementia. Um, these are all ailments that
at their core have got an endocannabinoid, um, base. So let's talk a little bit more
about endocannabinoid deficiency. So these are aspects of a
dysregulated endocannabinoid system, right? When the endocannabinoid
system is not making enough, uh, andogenous cannabinoids, which means
cannabinoids that are made in the body, um, it doesn't have enough signaling
molecules to go around the body and, and do the work and to
regulate these systems. And, you know, if you, if you refer to
Dr. Ethan Russo's original paper on, uh, endocannabinoid deficiency, and you look at the causes for
endocannabinoid deficiency, it reads just like a normal day in
America, listen to this. These are, these are the five, uh, big things.
So number one, environmental toxins, number two, pharmaceuticals that repress the immune
system or intentionally dysregulate the human body in some way, like chemo being
an extreme example. Um, but, you know, antibiotics are another example. So
it doesn't, it doesn't take much. You're just, we're just talking about
any pharmaceutical that's
gonna be repressing normal, uh, endocannabinoid operation, poor sleep, poor nutrition, and stress.
Well, my gosh, that's, that's just the modern world. So, um, it is very likely that most, if not everybody in the country has
got an endocannabinoid deficiency. And that explains why we've
got this is, you know, such a terrible situation with, uh, so many people getting
sick in different ways and, and having weakened immune
systems, which, you know, cause us to walk around our lives
with heightened anxiety and, uh, susceptible to all sorts of,
um, you know, disease and virus. So, you know, when teaching
specifically about C B D, cannabis medicine in general,
but really about cbd, some people become skeptical asking
how can one supplement help so many different ailments, but it's really just one thing
that CBD supports, right? And that's the endocannabinoid system, but that system touches
nearly everything in the body. So when we add a cannabidiol
c b D as a supplement, it just makes sense that if you would
strengthen the body's self-regulation system, that you would also empower the body to
make the changes it needs everywhere. So this is why they say,
oh, you got migraines cbd, you got irritable bowel
syndrome, you got, you know, cbd, you got poor sleep cbd, you got pain
cbd. It's like, ah, come on, man. Like, it can't be a panacea. But it is. And it isn't like it really does
help alleviate all of this suffering, but it's really just because
it's helping one system. And that system is the
endocannabinoid system, and that's the master regulatory system. So it's really just a
matter of perspective. Um, if you wanna learn more about this, uh,
firsthand from Dr. Ethan Russo, his, uh, seminal paper on that
from 2004 called Clinical Endocannabinoid Deficiency, um, is
available easily for free online. And if you go to the, uh, shaping Fire
website for this episode number 100, um, I've got a link to it, uh, for you
there. Um, also if you want to hear Dr. Ethan Russo talking about endocannabinoid
deficiency in medical cannabis, I actually did an interview with
him about endocannabinoid deficiency a long time ago, back in, uh, 2015, um, when I was still a partner
over@goentrepreneur.com and hosting the Go entrepreneur.com podcast. So if you go over the to
preneur.com into 2015, um, you can find my interview with Dr. Russo there before I left
Entrepreneur and started Shaping Fire. Um, you can also read a very helpful
article on endocannabinoid nutrition, um, from 2016. Um, actually
it's not an article, it's another interview I did
with, uh, Ethan Russo, um, at Entrepreneur again. So, uh, I did a, I did a full year of weekly
episodes for them, like, I think I did like 54 episodes
before, um, before I wished them well, and came over and started, uh,
shaping Fire. So, so in 2016, that episode's called Endo
Cannabinoid Nutrition. And, um, it's probably really easy
if you just, you know, Google endocannabinoid Nutrition, Ethan Russo entrepreneur,
that'll get you there. Um, also, uh, more recently though, uh, if you want to learn more about
endocannabinoid mechanics, I also recommend shaping
Fire episodes 78 and 81, and they're both with Dr. Miab Shields,
who is an endocannabinoid researcher. And, uh, we talk in detail about
endocannabinoid mechanics and, um, you know, kind of the endocannabinoid
system in depth. And, um, and Miab is, uh, absolutely,
uh, a fantastic guest and, um, a, uh, pharmacologist and really
understands, um, you know, the, the biochemical, um, workings of, of the human body. So, all right, so,
so let's move on to the next section. You can always look up more on the
endocannabinoid system, but, uh, I think that that is a good enough
explanation for, for most folks, uh, to get a good picture of it in their head. So the next thing we're gonna talk
about is a method of use, right? How do you get the, um, uh,
cannabinoids into your body? And so, so how we jump from endo
cannabinoids to using the cannabis plant is pretty simple. Um, I mentioned
that the endo cannabinoid system, uh, creates and manages, uh, cannabinoids. And when they're made inside the
body, they're called endocannabinoids, cuz they're endogenous to
the body. They're, they're
germane to the body, they, they come from the body. Um, but if your body is not
making them because you have
endocannabinoid deficiency, you've gotta get them elsewhere. And then you've got to put them in your
body to strengthen your endocannabinoid system, and hopefully you'd
be able to decrease those, um, those five things that cause
endocannabinoid deficiency, right? So that you can start making your own
again. Um, in the interim, you're gonna, you're gonna supplement with
phyto cannabinoids, which are, uh, cannabinoids that come
from plants. So, you know, your long term goal is actually to
take phyto cannabinoids from cannabis, but then also go back and,
and fix as best as you can, the five things that cause endocannabinoid
deficiency, right? The poor sleep, all right? Get better sleep,
poor nutrition, eat better
food, eat fresher food, don't eat as much processed food,
environmental toxins. Well that's pretty, that's, that's pretty difficult if
you live in the city. But, you know, do what you can to decrease
environmental toxins. And then, um, uh, decrease the, the, you know, as much as you can the pharmaceuticals
in your life that are screwing up your endocannabinoid system, which, uh, for, for many of these ailments we
take pharmaceuticals for, um, we would be better to take a cannabis
medicine full of phyto cannabinoids to strengthen our endocannabinoid system, to let the endocannabinoid system solve
these issues for us instead of taking, um, more radicalized
pharmaceuticals, um, that often have, um, uh, unpleasant, um, side effects. So, so we want to get phyto
cannabinoids into our body and, and those are in the plant. And so, um, let's talk about the different
ways that you can, um, take, um, the cannabis plant into your body. Let's start with the most common way
that people get cannabis into their body, which is by smoking it. So, um, while the most traditional and
accepted way to use cannabis dosing from smoking cannabis
plants is hard because it's very inexact, and often patients don't have proper test
results for whatever they are smoking. Um, the inexact part is that you, you don't know how much of
the flour or a joint or a bowl or bong to smoke to get the
dosage that you're shooting for. If you're, if you're shooting for
five or 10 milligrams of, of thc, um, you know, it's, it's a very, you
know, it could just be, you know, another, an extra two puffs that take you from
where you wanna be to actually being more medicated than you want to be. And, and
you've missed the zone that you want, that you want to target, um, to
help you with your ailment. I mean, we've all had the experience of, of wanting to have a little puffy
puff before we go somewhere, and it ends up coming on a lot
stronger. And then we're like, oh, I guess I can't leave right now. And you have to wait to come down a
bit before you go. Well, you know, if, if you're in the social time of your day
and you don't have a lot of pressure on you, well, that, that's, that's
fine, you know, you can do that. Um, but if you've gotta like get, you know, if you're in a lot of pain and you
have to get to work, if you are, uh, if you're having a lot of suffering and
you have to stay sharp to take care of your kids, you know, really, um, smoking may not be the way to
go because it is so hard to titrate your dosage and know exactly
what you're taking. Also, you know, the, the, the, the, the most patients don't have test
results for the flour that they're smoking. Most folks don't get the flour
that they grow at home tested. Um, most folks don't get, um, uh, analysis, testing, um, when they buy
their weed from their neighbor. And, you know, if you're, if you're
shopping at a medical or a licensed, um, you know, recreational store, you know, they may or may not have
the analysis on hand. Some states they don't have to
have it there, they just, you know, need to have it back at the original
grower and you can, you know, email them for it, right? So a big difference whether or not it's
available in the store or if it just like theoretically exists in the
world, and you could ask for it also, just because, you know, the, there is a certificate of analysis
in the store and you can look at it. That doesn't necessarily mean those are
the ratios that are in your particular flower. Um, you know, they're different parts of the plant
will develop different cannabinoids. So the things on the top
that are going to the, the flowers on the top
that are getting, um, uh, longer and more intense sunshine, they
will develop different cannabinoids then, um, flour that is, you know, more in the interior or on
the middle or towards the low. And so different parts of the plant are, are actually going to be different
medicine to some degree. Um, also smoking cannabis results
in cannabinoid conversion. Um, you know, it's, it's, it's kind of a myth that the lab
results that you are getting about your flour is showing what exactly
is going into your body when you smoke it. Um, we know from significant research
that when you combust, um, the, the, the flour, the cannabinoids convert to
different cannabinoids often. And so, um, you get this, um,
you know, cannabinoid drift and, um, you would only know what you're actually
getting in your smoke by testing the smoke, which is not something
that's available to nearly anybody. The reason why smoking is, you know, move so fast is because
when you inhale the smoke, your lungs are very efficient at,
um, at bringing in cannabinoids, um, through the, through
the lung, and, um, it's very quickly in the blood
and then it's very quickly, um, to your brain and distributed around
your body. So it's just the fastest. And so as soon as you smoke, you know, within the first 10 to 15
minutes, you take this fast, fast ride up, this rollercoaster, and then you slowly start to, you
know, come down over time. Um, whereas, uh, you know, when you
are using a different method, which we'll talk about, you're not,
you're not going up really fast. You're going up at a measured pace, and you're coming down as a
measured pace and for repeatable, for results and for continuing to be
able to be productive during your day. This is what is called for, uh, most of the time for
patients rather than smoking. So obviously with the added caveat
that, um, you know, if you, uh, have got a, an acute situation
as a patient and you need
medicine now, you know, top of mind would be, uh,
severe pain patients, um, and some types of, uh, you
know, anxiety patients. Sometimes you need to smoke
now and you need the, the, the cannabinoids to hit your bloodstream
now. And for those folks, certainly, um, smoking makes the most sense.
Um, but generally speaking, for most ailments that most
cannabis patients have, smoking will not be your option
cuz it's, it's too uncontrolled. So let's talk about cannabis
oil. So cannabis oil is, um, the concentrated resin that is found
in the trichomes on the cannabis flour. Um, this is where the
majority of the medicine lives that, that we remove from the plant.
Um, there are, uh, you know, a lot of different, uh, solvents that you can use to
remove cannabis oil from the plant material. Um, over the years, um,
hydrocarbons have been very, you know, pop popular, um, butane propane, and, um, but there's been a lot of pushback around
that because not everybody knows how to purge, um, those hydrocarbons
from the oil correctly. And, and some of that can
end up in your human. Um, I much prefer, as does many, um, uh, medicine makers to use ethanol because
ethanol does a really good job at, uh, removing, uh, the, the vital components of
the resin and, um, is, is quite easy to, uh, remove after
the fact, um, by just adding, um, a small amount of heat and the
alcohol just vapes off. So, um, it's, it's pretty hard to get into
trouble with ethanol and, uh, is is certainly what is most called
for for home medicine creation. But honestly, I've got a lot of respect for licensed
companies that use ethanol too. Um, because even though it's a, it's a
little bit more, uh, laborious than, um, you know, hydrocarbons often, um, uh, I think it gives a much
better snapshot of, of all of the healing potential
that is in, um, the resin. So, um, so yeah, a lot of people call it
rso, Rick Simpson Oil. Um, you know, while Rick Simpson, uh, deserves some respect for
popularizing rso, um, you know, it's not like he invented
it, you know, um, he did bring it to a larger audience
and for that will ever be grateful. Um, but, you know, a lot of his original
recipes, you know, when we look at now, um, you know, they're using
dangerous solvents. And so, um, that was a little sketchy, but,
you know, building on what, um, Rick made popular, um, there are now more modern processes
that, for example, use ethanol, uh, which is the primary solvent use nowadays. And so we all still kind of call
it RSO because that's what people know it first. Um, but um, it's been a whole bunch of other names
have been tried to be given to it. Um, another popular one is feco, uh, full
extract cannabis oil. Unfortunately, FECO sounds like fecal
though, right? I don't, I don't think fecal is ever gonna
like, catch on fully nationally, but full extract cannabis oil that, I
mean, that, that sounds good, . Um, and, uh, and, and so some companies have tried to name
their process different things, but, um, I'll probably sometimes accidentally
say RSO during this episode. Um, but I usually just, uh, I just
usually call it full, full, uh, extract cannabis oil and just say those
words and don't usually use fico. But, um, but now you're at least familiar
with the terminology. So, um, one of the reasons why using,
uh, full extract cannabis oil is, um, is, is probably at the top of the list
of what to use as a patient is because once the oil was made, um, all of the oil is pretty
uniform and homogenized. Um, it's not like, oh, this
part of the batch, um, has got these cannabinoids and this
part of the batch has got these other cannabinoids. Um, once you have, um, soaked the cannabis in the
ethanol and then gone and vaped off the ethanol, the the sticky resin that you're left
with is pretty homogenized and it's all the same. And so when
you go ahead and you, um, send it off to a cannabis lab to have the analytics done, you know that those analytics
are representative of all of the medicine in the batch. And you can compare that to
what we were just talking about, about cannabis flowers, where, um, the
flowers that are at the top, middle, bottom or interior of the plant will
all have slightly different, um, cannabinoid profiles. Um,
but by the time it's in oil, because it's all been put, you know,
it's all been soaked and, and, um, vaped off together, your oil
is, is essentially uniform. And that's great. And, you know, if, if you happen to live somewhere where
you don't have access to a cannabis lab, at least you know that when you, when you take your first trials of
your oil to see how strong you made it, once you've, you know, you've taken it
three or four times and you're like, okay, I know how much I need
as a patient of my stuff. Um, it's gonna be like that for the
rest of the, that oil that you take. It's not like, um, you're gonna take the
first couple and you'll be like, okay, I now know that I need, you know, 0.05 milliliters of this oil for the medicinal experience that
I'm looking for only to like, take that same amount four days later.
And you're like, oh my God, I'm so high. Like, that's not what medicinal cannabis about
is about medicinal cannabis is about repeatable results that you can rely
on to improve your health and improve the strength of your endocannabinoid
system and allow you to take cannabinoids while you can still function in life
by, by, you know, going to work or, or taking care of your family, or
I don't know if you're bad enough, just live, right? So, um, we're
looking for repeatable results, and that is one great
aspect of cannabis oil. Another thing that's great about cannabis
oil is, um, you know, when you're, when you're buying flour, um, flour costs money. If it's got any part, it costs more money if it's got
any sort of bag of peel, right? So the, the least expensive flour to
buy is flour that is ugly. And I don't, I don't mean all molded
and and such, but I mean like, like mids and lowers and stuff that
was trimmed badly or wasn't trimmed at all. Like, this is the best stuff to be
making cannabis oil out of, and it also happens to be the cheapest
stuff in the market. And so, um, it's not, it's not uncommon for a, a home grower to take all of
the tops off their plant and, and cure them and either keep 'em or
sell them and then take all of the, the lowers and either
process it themselves or, or give it to a loved one who's a,
a patient to make into cannabis oil. And so, you know, back in the day,
you know, we used to call that trash, and so people would all like, where'd
you dump your trash? Because all, all of those, all that trim
that came off the plant, uh, people weren't really doing
extraction yet. And so, um, people were just trying to play find
places to dump it where no one would find it and, and bust them back in the day.
And then, then all of a sudden, um, people started, uh, blasting bho in their backyards and
trim became like, really valuable. And then, you know, we've just evolved from there that we
now use every part of the plant. And, um, we're not gonna talk about
making cannabis oil today, but I just want you to
understand that, um, the advantages of cannabis
oil in its, um, uh, consistency of analytical results
throughout the batch and the fact that once you put it
in a capsule and take it, your body will process the capsule
and, and take the cannabinoids in. And then you will slowly
feel, um, you know, the cannabinoids or not
feel them depending on the
dose that you, you choose. And you'll slowly have an inten
intensity of cannabinoids and it'll slowly go down. And that process usually
takes between three to four hours. So a patient who is, uh,
doing a cannabis oil protocol, um, will often take their capsule every
three to four hours, depending on, um, you know, their needs and,
and what they can afford. Um, the last thing I wanna say about the
cannabis oil is that, um, you know, because it's usually, um, offered
in syringes, like oral syringes, um, it's also quite easy
to make, uh, capsules. Um, most folks will pick up, um,
one milliliter capsules on eBay, excuse me, one milliliter syringes,
oral syringes on eBay. And, uh, you make your oil at home and you fill
your syringes. And then the, uh, the, the, the nozzle, the nipple non nozzle on the
one milli milliliter syringe fits really nicely into a
number three size capsule. And so it, it makes making your capsules really
easy and the sides of the syringes are marked. So you know whether or
not you're putting in, you know, 0.05 milliliter or 0.1 of a
milliliter, which is, you know, usually where most people are.
Um, and, uh, and people can, uh, take it by there. Um, one note, if you
are going to buy your own capsules, um, uh, I recommend that when
you buy them, buy them separated. I went years before you could, before I realize that you could buy
your capsules separated. And so I, I would just buy bags of capsules
that were, that looked like capsules, then I'd have to separate them
all by hand before I filled my, um, my capsules with the
oil. And I gotta tell you, when I was first starting making my
capsules after I got my dual concussion resulting in a traumatic brain
injury, um, like that was, that like filling capsules
was mentally a lot of work. And so I wanted to make the
process as slow as possible, and it would've been really nice to
have known that I could have just bought caps that came in, two bags separated.
So, um, so there's pro tip for you. Okay, let's talk about
tincture now. So, um, one of the interesting things
about tincture is that tincture is at its most essential cannabis
oil that we just talked about, suspended in ethanol. Um, because, uh, when you make the cannabis oil, you are using ethanol to
extract the resin components from the trichomes on the
flour with a tincture. What you have is the
cannabis resin suspended in ethanol, which is what's
used to extract it. Um, now it's certainly true that some
people will add, um, you know, uh, vegetable glycerin or coconut
or honey or a lot of other things to adulterate the oil to make
it more palatable, right? Because, um, a straight ethanol tincture, I mean,
that's got, that's got some bite to it, right? Um, I normally tell patients that if
they're making an ethanol tincture to be prepared to just, you know, take their dose and put it in a little
bit of water and then just drink the water. Cuz you know, if you're, if
you're gonna be using, you know, food grade ethanol at 190 proof,
say for example, ever clear, I mean ever clear burns most people's
tongues, right? And so, um, you know, just putting it, putting a little bit of water in a
sock glass or a shot glass and then adding your tincture to that will
make the ethanol a lot more palatable if you happen to be in recovery from
alcohol. And, um, you, you know, are, you're not, you, you have chosen to not
have any alcohol at all in your life. Um, what many patients do is that
they will make a, uh, hot tea, not boiling, but just like hot tea, and then they'll put their tincture
into the hot tea and the tea just like let it sit for a couple minutes
and the hot tea will vape off, um, you know, the ethanol aspect of
it and will just leave the, uh, cannabinoids the resin, uh, in the
tea. And then you just drink your tea. And that seems to work for them. Um, so, so one of the things that's great
about tincture is that when you put the resin into the ethanol, um, once you let it sit for a little bit,
it will, uh, self homogenize, it will, uh, become ubiquitous,
uh, throughout the jar. And which means that, um, if you, if you make your tincture and you strain
your tincture and then you let it sit for, you know, a day and, and
let it come to, I don't know, I wanna say homeostasis, but I don't
think that's right. But if you wanna, if you give it time to
self homogenize, um, uh, you can go ahead and, and, and take
a sample out of it. Um, you know, I like using a Turkey baster.
Take a sample out of it and, and put it in a little one ounce
bottle and send it off to your, um, cannabis lab. And you'll
know that the test, that test results that
come back apply to, um, the entire jar of tincture that
you've made. And so, you know, that's the same thing I like about
cannabis oil, right? That it's, that it's uniform and it is one of the
biggest problems with smoking flour. Cause that's not uniform.
So, so tincture we like, because it's really easy for
anybody to make. And, um, you know, if you don't add the adultery and, and I don't add any adultery to the
stuff that I make for myself and, um, the stuff that I make for my
parents because, um, you know, as we get older, it is more difficult to
shake a bottle of tincture. And if, and if you've got, you
know, cannabis resin in there, maybe a little bit of ethanol
and some glycerin, uh, those have all got different weights
and they will not be uniform in the, the, in the tincture bottle.
And so if you, if you, you know, give it the kind of shake that you, you can imagine you do with a
tincture bottle, like you, you, that's not gonna homogenize it,
right? You're just gonna like, kind of mix it up a bit. Um, but that means that if you are
taking a tincture that has got THC in it, which, um, you know, can
and can, can cause intoxication, um, you will not be getting
consistent doses, right? If, if one, um, if one squirt of the dropper is
usually gonna be five milligrams and, and your tincture has got, you know, honey or glycerin or something else,
you're gonna get, you know, you, your, your your drop or could have
anywhere between like, you know, maybe two to eight
milligrams of THC in it. Um, and that's a, that's a really
big swing for, uh, most patients, especially new patients.
And so, um, so yeah, uh, and a lot of the, you know, a lot of
folks can't, they don't have the wrist, you know, to be able to, to
shake it anymore because,
um, they've got arthritis. So, so, you know, if you're making your own stuff
and you're making a C B D and like the, the actual amount at any particular
time doesn't matter as much as you making sure you take it four times
a day and making sure you get a daily dose. Well, sure, you know,
put glycerin or, you know, agave or honey or whatever
with your c because having each dose be exactly the same, it's
not really as big of a deal with cbd. Um, but with THC it
does because if, if you, if you go too high, um,
you know, you may get, uh, more THC than you are prepared
for at that part of your day. Another thing that's
great about tincture, um, when it's in ethanol is that
it's, uh, shelf stable, right? And so for a lot of patients, um, you don't have an opportunity
to make tincture all the time. You might grow your few
outdoor plants every summer, and then you're gonna
wanna, you know, you'll, you'll choose to process
that into tincture and that
tincture needs to last you a whole year. And, um, you know, uh, cannabis oil and tincture and
ethanol are both, you know, quite shelf stable if you keep
them out of the sun and cool. Um, and, uh, cannabis oil specifically
does pretty well in the crispr. Um, but if you're putting
your, uh, you know, you don't have to do that
with the tincture as much
because of the ethanol. Um, you can either just store it in a
mason jar in a dark closet or, um, if you, if you wanna stay, keep
strict controls over your use, you can put it into one ounce tincture
bottles that you can pick up online for places from places like specialty
bottle.com and then just, you know, um, fill those bottles for yourself,
label them and put them away. And for a lot of people, um, managing their tincture use that way
is very visual because, you know, like, okay, I've got, I, I've made 30 bottles and this
has gotta last me the year. And so you, you can just see them in
the box and as the box gets lower, you've got a really good, um, visual example of of how
much you've got left and, uh, and, you know, if, if you should be getting nervous and
maybe figuring out where to get some more flour to make some more or, uh, more
hopefully you're just re you know, reinforcing the peace of mind that you
are a self-sufficient cannabis patient and, and you can take care of
yourself and you got what you need. So that's great. Another thing
that's great about tincture is, uh, being able to, uh, control
and fine tune your dosing. So with the cannabis oil that we talked
about, and certainly with smoking, um, with cannabis oil, because
the oil is concentrated, um, it's harder to hit low
numbers. So, um, you know, most of the time when I'm
talking to patients, if, if they, if their need is only for
five or 10 milligrams of, um, of thc, it makes sense that they
are going to use a tincture. Because a tincture, you can, you
can get it down to, you know, number of drops out of the dropper
if you want, whereas with oil, you know, which is essentially the resin without
the ethanol that's in the tincture, um, you know, it, it's
kind of hard to, um, extract resin from a
plant that's high in THC and get your doses dose down
to five or 10 milligrams. You know, you might,
you might, um, you know, at 0.05 milliliter, which
is a usually one of the, the smallest markings on a syringe, you might already be up to
like 17 milligrams of thc. And so when it comes to thc, um, I'm usually recommending that new
patients to THC focus on tincture. But if you have a very significant
ailment in your, um, your, your tolerance is very high because
you're taking a whole bunch of THC every day, well, you've probably
graduated up to cannabis oil. Now that, that's different if we're talking
about C and CBG, where, um, you know, if we're gonna, if we're
gonna grow a plant that has cbg, we, we might use tincture so that we
can have, make it last longer. But in most cases you're, you'll
probably make an oil, um, because, and then just make caps with,
you know, 0.05 in it, um, because it's just more convenient
and you don't have to use, keep the, the ethanol in the tincture bottles
and you can pre-make a whole bunch of capsules because the difference, you
know, whether or not you take five, 10, or 20 milligrams of cbg, um, it won't end up in you potentially getting
intoxicated like it would if you were taking thc. So, um, you know, when I make my CBG caps, um, I'm
a little more casual about it. When I make my THC caps, I'm very exacting because I don't want
to accidentally over medicate myself. But if I'm making CBG
caps, well, you know, I might watch TV while I'm doing it
or something, right? Because, um, if I squirt a little bit
extra in, um, it's, it's, it's not really going to be,
um, you know, bad in any way. I might be a little
wasteful, um, but it, but it, but it's not gonna make me
super stoned. And so, um, this is one of the reasons why
tinctures are good, because, um, once you have, once you've got test results
and you know how much is in one, um, one dropper of your tincture, if, if you wanna take a little bit less, less one day or a little
bit more another day, you can totally make those changes
on the fly. And it gives you, you as a patient a lot of control.
And, and that's what, you know, that's what we want. Um, some days
you might wake up and you know, you have to go to a doctor's appointment
and so you want to go a little bit more conservative on how much
THC tincture that you take, cuz you know that you're gonna have
to interact with people in an hour or something or maybe drive
there, right? Um, but, but on another day you may have slept
really badly and you are experiencing, um, your ailment significantly and you
don't have anywhere to go and you might triple your dosage cuz
you're like, you know, all I'm gonna be able to do today is,
um, sit on the couch and, you know, try to, try to not be
miserable. Well, you know, that gives you that kind of flexibility. If you've already made all of your
oil into capsules, well, you know, unless you've made
different potency capsules, all your capsules are gonna be the
same strength. And so that is a, a great reason that, um, you know, tincture can be a superior
choice for patients. So let's talk about edibles. So,
um, edibles have got a place, but I gotta admit that I am not the
biggest fan of edibles except for specific kinds of patients. And, um, first
I'll talk a little bit about, um, why I tend to recommend cannabis
oil and tincture over edibles, but then we'll also talk about, about why edibles are the perfect
thing for particular patients. So first of all, um, edibles are usually
non-homogenized and, um, or, or poorly homogenized, right?
Um, which means either, either at home or at a,
uh, at a licensed, um, cannabis bakery, they are
infusing an oil, a fat, a butter, um, with cannabis, either the, the flour or an oil or some, or
an isolate, I guess. And, um, and they're mixing that into the oil. And then you add that oil
to your recipe of whatever you're making for, for the
sake of this discussion. Let's say that they're making
brownies since that's so traditional. And so you mix it into your brownies and
then you bake your brownies. And, and, and, you know, most of us
who have been, you know, using cannabis for a few decades, we've all had the experience
where you make a batch of brownies and the first
brownie you have is a, uh, different strength than the fifth brownie, which is a different strength
than the 10th brownie, right? Because it's kind of just luck
of the draw where how much oil ends up at different
parts of the brownie pan. And so you could eat one and it could,
you know, you, you, you're like, okay, I know that if I eat, you know, a half a
brownie, that's about the right amount, and then you go to eat
a different brownie, and that half a brownie actually has
got a whole lot more oil on it just from luck, you know, from randomness.
And now suddenly you're like, you know, really high and you need to go
lay down, and you're like, damn. Um, I really thought that all those
brownies were gonna be the same strength. And that is very, very hard
to do with baked goods, um, especially in the home, right? Like, like this primarily happens when people
share the cookies or whatever that they make at their house. And, um, you
know, they're, they're moving along, and they, they just mix the
brownie mix or whatever, um, until it gets the right consistency, well, it being the right
consistency may not be also homogenized. And suddenly now you're making brownies
that where each one you have is a lottery ticket to being
too stoned. So, um, uh, that is, that is one significant
issue with edibles now. Now, certainly in the commercial markets
where they are increasingly using, um, isolate and they have more control
over their processes, um, you know, they're a lot of these 10
milligram, uh, gummies, for example, they're quite, you know,
homogenized. Um, you know, unless any company that's got a
worthwhile lab and kitchen is doing a pretty good job putting those
together, so there's not huge swings. Um, but that's not true, man. You, you
get a, you get a company that's, that's newer or have less,
less experienced employees, um, or you know, what's happening as, you
know, some states go medical, right? Because you get all these people who are
trying to go professional for the first time, and they, they, they made, they
made edibles at home, right? For their, and, and now they're
suddenly trying to scale up, but they haven't learned their
lessons and best practices yet. And so suddenly you've got a new company
in a medical market that's putting out edibles with wild swings,
um, with their potency. And, you know, they'll get complaints and
they'll get best practices, and, you know, eventually with time
they'll be more consistent. But if you're buying from them
at a medical shop, you know, early on in your state's process, uh,
chances are very high that you're, you're gonna get something that's
got a certain level of risk to it. So that's homogenization also, um, for many of the patients
that I talk to, um, they're not in a position to be taking
on these extra sugars and flowers and artificial colors, and sometimes even artificial
flavorings that edibles have. Um, especially if you are, um, you know, an advanced patient and you need
edibles, you know, four times a day. Oh my gosh. Like, let's go back to
the brownie example. Like, like, you shouldn't be having a brownie
four times a day or a cookie, or probably a gummy.
And, um, and, you know, you may decide for you that
that's okay, and that's cool. Like we're all our own empowered patients, but I'm talking about general best
practices and generally speaking, the edibles that are, are available, you're not gonna be wanting to eat them
four times a day or maybe even every evening before you go to bed, right?
If you're taking it for insomnia. So you gotta be really
aware of, of the, you know, what your cannabinoids are
encapsulated in, right? Are they, are they surrounded by, you
know, sugars and GMO flowers? Um, certainly there are really healthy, um, whole plant resin edibles
out there. They exist, but, um, they, they almost always cost more because
they're made with quality food products and, um, and, you know, they
might not have 'em by you. Um, so the next thing we're gonna talk about
is the delayed effect due to digesting, right? So, um, in, in our first example when we were
talking about smoking at top, one of the great things about
smoking is that it comes on so fast. You've got all, you know, you, you're
peaking on your cannabinoids in your, in your bloodstream at, you know, 10 to
15 minutes in, um, that's super fast, right? Um, edibles are the
opposite, right? Because, uh, you're gonna chew it up and
then you're gonna swallow it, and then it hits your gut, and
then it goes through your liver, and then now it's in your, um, blood. And so it comes on, um, you know, most people say between
30 to 45 minutes, but for, but everybody should be
aware that sometimes you do
get a, a, a sneaker edible, and it takes a while for your body to
process it. Maybe, maybe you had a, a meal earlier, and so the edible is actually behind
all the other food that's gotta go through you. And so, yeah, sometimes
it does take two hours, but you know, that's, that's, that's, that's pretty rare compared
to like 30 to 45 minutes. Um, and so if you need relief now, waiting for 45 minutes may not
be the right solution for you. So that's something you gotta weigh
for yourself and your own needs. Um, also one thing that's
interesting about it is that, um, when THC goes through the liver, it changes to 11 hydroxy
THC in the liver. Um, which means that, you know,
even though we're, you know, we're talking about cannabis and
even though we're talking about thc, it's really a different form
and it, um, it feels different. It acts differently on the body.
And so this is probably, um, where the, the best benefit of edibles
comes from because there are certain patients, um, I would put at
the top of the, the list, um, uh, uh, pain patients, um, rheumatoid
arthritis patients, and, um, uh, pretty much any of the
inflammation, uh, diseases, lots of, um, uh, immune compromised folks. They find that the 11 hydroxy
THC experience that comes from an edible is far superior to them, then a Delta nine thc, um, preparation. And, um, so you'll have to
find this out for yourself. Um, you know, 11 hydroxy THC is not going to be the choice for most patients, but for those that it
works better for, um, they become very serious about
their edible consumptions and making sure that they are finding the edible
that they can make homogenize that is low in sugar, that they can eat the smallest amount
of edible and get the more profound effect. Um, and it, and it really does become something
that the patients are dedicated to. So, um, so yeah, sometimes 11 hydroxy THC is the, is the
way to go, and you'll just have to, I, if you are that patient, you will, you
will come to that realization yourself. I just wanna let you know that it's there.
So, um, so that's edibles, right? Um, a a very common way to take thc, um, but also probably not
necessarily the best for most patients, if you're gonna
be taking it every day, because you can take a
tincture or a cannabis oil, um, that's not gonna have any of those extra
sugars and flowers and colors. Oh, my, okay, the last one we're gonna talk about
is suppositories. And, uh, you know, suppositories are not used all
that much, um, because usually, um, um, you know, taking your cannabinoids orally is
gonna be appropriate for just about everybody. Um, but I have certainly worked with
patients who came to me because they were having problems, uh, taking their cannabis oil orally
because they had something going on that was, um, you know, chronic
and dastardly with their gut. Um, say for example, that their, their gut was dysregulated and
they were not creating, um, digestion enzymes properly.
And so, um, you know, putting anything into their gut
was a really bad experience. Um, or potentially, um, they have
something going on in their gut, so they can't take any fats
or oils into their gut. Well, you know, it's true that cannabinoids in cannabis
oil are really great for the gut, but if the vehicle is an oily
resin from the plant, um, you know, some patients, they can't be taking
any oil into their gut, and so, or else you know, it, it causes, um, you
know, lots of grief and suffering. So, so that might be a case as well. Um, I'm sure that there are other ones that
I haven't come across, right? Like, you know, potential, uh, ulcers or
lacerations in the gut that, that, you know, you might not want
to get oil in as well. Um, but for some people, they,
they need to, uh, skip the gut. Um, also there, there are some other, uh, ailments that, that suppositories are
just a great idea for, for example, um, for mittal cramping, right?
For menstrual cramping, um, you can use a suppository either in
the rectum or in the vagina, and, um, you will get more targeted
placement of the cannabinoids to relieve your symptoms. Um, if you are gonna put cannabis
oil in, um, a vagina, be really careful about
the amount you use, um, because you don't want to throw off
the pH and, and cause other issues. Um, luckily we don't really have
the same kind of, uh, pH issues, uh, for the rectum. Um, also
rectal cancer, right? If you are, uh, you know, if you are
dealing with, uh, uh, tumors or, or, uh, such, um, in the rectum, a
placing the cannabis oil right there, um, um, is going to increase
the level of, you know, targeting that you can do for it. And
then also if you've got, like, you know, just general hip pains,
right? If you've got, if you've got pains or discomfort in,
you know, in the area between, say, your belly button and your thighs,
right? Like that whole area, applying it to the rectum may be
a solution that works for you. Now, granted, most people are going to
take it orally, and it can work great, but, um, you know, this
is where you decide, because every patient works out their
own protocol in the end. Um, you, you, you know, you, you learn these things
from people who have done it before you, like, I have, but you know, you do this for two weeks and now you
are gonna become the expert on your body. And that's what we're,
that's what, you know, good cannabis educators are gonna do,
is give you all of the options and say, choose what works for you. Um,
instead of saying, all right, I have the solution for all
patients because, um, you know, each patient is unique,
just like growing, um, different types of cannabis are
unique, you know, uh, and, uh, and we need to, we need
to treat each person, um, in a way that works the
best for them. So, um, if, if you've decided that suppositories
are something that, um, that might be appropriate for you, there's lots of great kits out there
for making your own at home. Uh, on, for example, eBay, um, uh, they,
they sell these little molds, um, that mold them into like a, like a
little suppository, like a football, you know. And, um, there's a bunch of
different recipes, uh, that you can, um, that you can use. Some people use shea
butter, some people use coconut oil. Some people use a combination
along with a little bit of, uh, full extract cannabis
oil. And, um, you know, people find what they like. Some people won't use Shay at all
because they don't care for it. Uh, some people will have different,
uh, percentages of each, right? Um, and so what you do is, you,
you would, you would make up, you'd fill up these little molds with
whatever you're gonna put in your suppository, and then you put 'em in the
freezer, right? And then they get hard, and then you pop 'em out, like ice
cubes out of an ice cube tray. And, um, and then when, when it's time to dose, you just like pop one of those
outta the freezer and you, you put it where you're gonna put
it. And, um, um, you know, , it's, you might be cold for a moment,
but, uh, it doesn't last long. It's not like they're that big. And, um,
and then it, it melts where you put it. And so, um, that can be a really
great win for, um, a lot of folks. Um, that said, it doesn't
have to be that much work. Um, when I was first learning about
suppositories and practicing with them so that, um, I could, um, teach
it to patient groups, um, I went through that whole process and I'm
like, oh my God, this is so much work. And, um, you know, it's so like, kind
of oily and everything on my fingers. Um, in the end, um, you know, I realized that you can also
just take a boring cellulose cap that, um, that you
would use for cannabis oil. You know, up in the cannabis oil
section when we talked about that, you can just put your, your cannabis oil in a cellulose cap
and put that in your rectum too. Ah, I don't think I would do that vaginally.
Um, I haven't had that experience. Um, but, but, um, but in your rectum
it works. And, um, you know, the, the, the fluid or that's in
your rectum will break down the, the cap. And, and then you will,
you'll, you'll get the oil through the, the rectal rectum wall, and
that works. Um, you know, um, but you know, most people do recommend against it just
because it's, it's kind of in elegant. But, um, but you know,
if you're, if you're, if you're a serious cannabis patient and
you are already to the point that you need to be taking suppositories,
you are probably, um, doing what you need to do and don't
really care about elegance anyway. Um, so by the time you're at that point, you're doing what you need to do to not
suffer. But, you know, there is, there, there are the great options cuz you know, there is nothing as luxurious as a
shea butter and coconut oil suppository , but, but you know, if you
don't have the time for that, um, or, or the money for the inputs,
um, putting it in a, uh, a vegan cellulose cap works
as well. Um, alright, so that, that was a great topic to
end this set on. Um, so, uh, so my goal at this point in the
show was for you to have, um, a really solid understanding
of the different methods, um, of cannabis, uh, intake, and a good picture for yourself
of the endocannabinoid system, why we are taking cannabis at
all so on from this platform. Um, we will now in the second
set, um, uh, go into, uh, specific cannabinoids and understanding
the amount of each that we would wanna take, um, to
reach different effects. So we're gonna go ahead and take
a short break and be right back. You are listening to the hundredth episode
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more sustainable plants. Pit moss. Welcome back. You are listening to the hundredth episode
of Shaping Fire, and I am your host, Shang Golos. During the first set, we talked about the endocannabinoids
and made sure you had a decent understanding of that, and then we talked about the different
methods of getting cannabinoids into your body. And so you're starting to get an
idea of how your body functions and the different ways that we
can add the cannabinoids, um, to meet your particular needs,
um, as a cannabis patient. So now on, um, set two, what
we're gonna talk about is, um, the specific dosing, um, for particular cannabinoids
that are commonly available and that we have actually got some
decent research on. So, you know, I'm not gonna go through
all of the cannabinoids that
exist because some of them we barely know anything
about yet. Um, however, um, we do know quite a bit about, uh, THC and cbd B D and we
know a bit about cbg and so we are going to cover those.
And the idea is that, you know, with those three, you can get well on
your way to, uh, relieving your symptoms. Um, and also once you understand how
to think about individual cannabinoids, as new cannabinoids become popular and
the research starts to come out, um, you'll, you'll have a good idea of how to think
through bringing a new cannabinoid into, um, you know, your health
protocol. So, you know, we have to start with a conversation
about isolates and whole plant, um, resin. Um, I would've originally,
and I would've been the old days, say that whole plant resin versus
isolates because historically I have not been a fan of isolates. But, um, over time as the quality from some
distributors have increased and, um, you know, some people don't have
access to certain novel cannabinoids. Um, it does, there is a
place for isolates, uh, in the health program of many
cannabis patients. And so, uh, I really can't, um, justify
writing them off anymore. Um, though it's very important to know what
their good uses are and where their limitations are. So, so first of all,
let's, um, let's go back a little bit. So historically people sought
whole plant cannabinoids simply because, um, it was the
only thing that existed. I mean, the people took the plant and they used
the resin as they got it off the plant, either by smoking the plant or, or, uh, mechanically removing the
trichomes and making hash, um, or, you know, as, as, uh, solvents were
developed, um, mixing it with, uh, ethanol alcohol. Um, so whole
plant was like the whole deal. But as technology evolved, um, the
creation of isolates became possible. And pharmaceutical companies were very
interested in isolating these compounds so that they could study 'em for
potential future healing products in the future. And, um, you know, if you're
not familiar with the term isolate, the isolate just means a single
molecule of the cannabinoids. So, so one single molecule of thc
or one single molecule of cbd, whereas in a whole plant resin,
you're getting a melan of, of different, um, cannabinoids
and flavanoids and, you know, fats and all these other things that,
that make for this particular synergy, which works so well with the
human body. So, you know, the first time I saw that
there was a really good, uh, reason to consider CBD is,
was in the early days of cbd, before CBD plants were available
just anywhere. Um, there was a time, you know, not too long ago, let's see, um, let's call it like seven
or eight years ago, um, where people started wanting C
B D, but getting your hands on, on plants that were bred with CBD was, was pretty challenging unless you lived
in California, you know, when you were, you were getting 'em from folks there
who were intentionally trying to spread them out. And so, um, we got to a point where people wanted
CBD and they especially wanted C b D in their cannabis oil concentrate, but it just wasn't to be had in any
kind of significant dosage. And so, uh, companies started
filling that void by, uh, extracting CBD single molecule isolate
from the cannabis plant and selling that separately as a powder. And, you
know, like I said, I was pretty, uh, pretty against that at the time as,
as being an overprocessed product. Um, but after I got over myself
and realized that, you know, you didn't have to take
CBD powder alone and, and we would eventually find out
that CBD powder is helpful for some applications, that the important thing was people
should have the understanding that they can spike their
regular THC dominant cannabis oil with C B D to expand
the benefits. A great deal. And I, uh, I remember
speaking first with Dr. Sunil Agarwal at the, uh,
Washington Cannabis Conference. I asked him while he was speaking
whether or not he thought that spiking THC dominant cannabis
oil with C B D to make it slightly more whole plant, right?
Since, since CBD used to be in, uh, land race plants, but we
progressively bred out over the years, so our cannabis plants were stronger
in thc. So, you know, a a land race, a natural plant actually has a
lot more C b D in it. Then, um, then the bread plants that, that are are used for
more recreational, um, uh, use nowadays. And he said,
yeah, he's like, he said, that would make sense to me, uh, to him,
Dr. Sunil Agarwal. And he said that, um, you know, until, until more plants can be evolved
that have a significant amount of CBD in them, and they can be
distributed across the country, if you can get CBD
isolate, go ahead and, and, and add that into your brew
when you are making your, um, your THC dominant RSO or cannabis oil. And I was caught off guard, but I
considered myself, um, you know, smarter for it. And then,
um, on an episode with Dr. Ethan Russo about five years ago, I asked
him the same question. He said, yeah, yeah, you know, if if you, if you need
CBD and you can't find whole plant cbd, well go ahead and, and take the
isolate and then spike your, your cannabis oil because your THC
dominant canus oil will have the thc of course. Plus it'll have a whole
bunch of those other, you know, um, flavonoids and can flavin and, and, and
novel cannabinoids and trace amounts. And then you're adding a, um, you know, he dose of C B D from the
isolate. And while, um, everyone agreed that, that when possible, it's always better to just extract the
plant and take the plant as is, um, you know, we don't live in a perfect
world. And sometimes you need to, sometimes you need to spike your oil
with a cannabinoid you need. So, um, so another thing that's, uh, interesting
to consider when comparing, um, ice isolates and the whole plant is that
in the early days of cannabis research, they were doing cannabis research
with the whole plant resin, right? And so the early studies that
you can look up when you, when you read what they were using and,
and how they actually performed it, um, they were extracting a, uh, a THC dominant resin and
experimenting with that. But as, um, you know, creeping normalization
started and, and companies, pharmaceutical companies started, um, uh, considering what pharmaceutical products
they were gonna make out of it. Well, suddenly the medical study
scientific studies started, uh, focusing more on isolate.
Because, you know, the two main advantages of
isolate are that number one, you do isolate the molecule. And so you can be sure, um, for repeatability of results
because, um, you can, you can make that isolate molecule
discreet from all the other components that are usually in resin.
And then second, you can't, um, you can't patent the plant. But if they made a medicine and they
made it out of isolate, uh, well, then they would be able to patent that
and call it a product and sell it, which is how you get
products likes ofx. So, um, so if you look at the, uh, if you
look at the scientific studies now, they are much more
dominantly using isolate now, um, to varying results. And, um, and, and one thing we know is generally you
need to take a whole lot more isolate to get the same kind of results that you
normally get with a whole plant resin. And, uh, and that when
you take isolate, um, it, your efficacy goes up to a point
and then it plateaus. Whereas, um, when you take whole plant because of
all the synergistic materials, um, generally speaking, the more you take,
the more reaction you're gonna get. It's worthwhile to note too that, uh, whether or not you want to use isolates
or a whole plant often just depends on how much money you've got. Um, there is no question that isolate is
far more affordable than a whole plant resin. Um, you know, your
mileage may vary with it, but if, if it's what you can afford and it
happens to give you benefit, we'll then, you know, you should definitely go for
it. Um, it's really interesting, um, as the market for cannabis medicines
and other fund products evolve, how odd the, the price ratios
work. So, for example, um, whole plant resin is
very expensive compared to isolate single
molecule. And so, you know, you need to have enough money
to be able to afford the resin. And when it comes to CBD resin, most patients their dosages as
much as they can actually afford, because they always want
more. And so in this case, the the resin is very expensive and the
isolate is very inexpensive. However, in contrast, if you are a cancer
patient and you are trying to use, um, THC to straight up beat the cancer, and you're taking a 90 day THC
protocol versus doing chemo, well suddenly now a THC
cannabis oil is very affordable, right? Because, you know, spending 1500 to $2,000 for, um, 60 syringes to take over 90 days, um, is very affordable versus a round of
chemo and all the associated costs of that. So, you know, um, we can't
jump to any conclusions about this is, you know, cannabis medicine
is so expensive, or cannabis
medicine is so cheap, or don't use this, or don't, we really need to think it through
for each patient what their unique needs are and what their
financial capabilities are. So yet another reason why, you know, we really don't wanna just group cannabis
patients into big buckets and tell them what's good for everybody, because,
because each patient is really unique. All right? With that discussion of
whole plant resin versus isolates, um, past us, um, let's go
ahead and talk about, um, the first cannabinoid we wanna
talk about in detail. And that, of course is the very popular thc.
And by that I mean delta nine thc, tetra hydro cannabinol. And so
this is the one that, um, you know, people have known about, um, forever.
And it's the one that if you take enough, um, you can get intoxicated. Um,
they referring to that as a euphoric. Um, but you don't have to take that much. And for most of the things that patients
need, um, you do not need to take, uh, enough that, that you will
necessarily get high. But, but let's talk about in in detail. So a THC strongly activates the CB
one receptors in the body and the endocannabinoid system
triggering a feeling of euphoria. And this activation also
increases the blood flow, blood flow to the prefrontal
cortex in the front of your brain, which is the area that controls your
ability to focus as well as your motor skills and attention and memory and like
your, your ability to make decisions. And then THC also interacts with CB
two receptors, uh, providing the, the analgesic or pain
relieving effect, um, also giving muscle
relaxation and antic effects, which is like helping
with nausea and vomiting. When we're thinking about THC dosing, we have to be really aware that there
are two different timeframes for thc. You've got, what can THC help with me
today and what will THC help me with over, over the time? So the short term effects of THC are,
number one, it's an analgesic that, uh, lessens and softens your
experience of the pain. Um, it's a distracting and meaning that you
forget about your ailment and you can focus on other things for
a while, like, you know, working or caring for the kids or focusing
on a fun activity. And, um, you know, when I say it's a distracting, it, it kind of just makes you forget about
the thing that you are suffering from, which is why it's especially
good for PTSD patients, right? They can set aside their, their memories of a trauma or of a
war zone or a of a bad experience, and for a moment be distracted
by the use of the thc, which allows them to do other things
that give their life, um, value. And so, and, and honestly, that's one of the I I'd additional
ways that THC is an analgesic, cuz like, not only does it soften your experience
of the pain and kind of turn down the volume, but then it distracts
you from it as well. And so THC actually helps with
pain in, in two different modes. It's also an
anti-inflammatory. And so, um, this is used a lot by people
who are experiencing, you know, rheumatoid arthritis or, you know, just regular arthritis or of swelling
or in inflammation of the joints. Uh, so in the, in the short
term, once you take some thc, those will go down temporarily as
part of the short term effects. We'll talk about that more in the
longer term effects. Um, as mentioned, it's also an amatic, um, meaning
that it decreases nausea. It's a muscle relaxant, which, which
decreases spasticity. And, and, and if you're unfamiliar
with that, that is the, the, the involuntary clenching of your muscles
that make your body feel all tight and stuff. And and we can apply this
to lots of different types of patients, right? Um, Parkinson's patients,
uh, who, um, have got tremors, uh, also Parkinson's patients who start
to get crampy and they, they start to, um, hunch over, um, people who have got pain pretty much
anywhere in their body because very often the other side of their body starts
to clench in response to the side that you're trying to, um, keep safe, right? You're trying to keep one side of
your body, um, out of harm's way, which means that your other side
of your body is doing more work. And those muscles, uh, tend
to get tight and annoyed. Um, and then also when you have
muscles that are relaxed, it decreases your experience of stress.
I mean, so often with stress, we, again, we clench our body and as
soon as we're like, ah, and you can kind of like open up
and your muscles feel relaxed, um, your anxiety will go down with
it and the thc, THC can, um, help with that as well. And then finally, it can help with sleep due to relaxation, because if you're having a hard time
sleeping because you're stressed out and tight and in your pain, um, you add some THC and suddenly your muscles
are relaxed and your pain is turned down and you're kind of
distracted from it, and, um, some varieties of THC can cause
drowsiness and lethargy will boom, there you go. It's gonna help
with, um, with your sleep now. And that lethargy can be
used for other things too, or combined with other things.
So if, if you were to get a, a THC plant that also is high in
terpenes like Meine or Lin Lu, which are both relaxing, um, you're, you're really setting up a good
combination for somebody who has insomnia, especially if they're insomnia
is compounded by discomfort when they're trying to, um, go
to sleep. It's also, uh, really good for people who are, uh, who have just had surgery because so
many of us, after we've had surgery, we're like, okay, I'm feeling better. I wanna like start moving around
the house. And we're like, no, you're supposed to stay in that
bed for a week and, and like, I'm supposed to bring you food
and, and people start to get antsy. But if you give them some, some
cannabis tincture, well, you know, they can, they can enjoy that lethargy, take more naps and like, you know,
be more easily entertained with like, color book coloring books and
crosswords and word searches and stuff. Stuff that just like keeps them
in bed so their body can heal. And the last short term effect of
thc, I'm gonna hit it here, is, um, as an appetite, uh,
stimulant. And, you know, we can all joke about
getting the munchies and, and sometimes it is very funny and
sometimes it's dangerous cuz we eat all of our food. But, um, but for folks who
actually are having a difficulty eating, um, perhaps because they are
going through, um, you know, a cancer treatment or some other
kind of treatment that, um, suppresses the appetite
or they're depressed or, or anything that's gonna
decrease the appetite, um, very often if you use cannabis while
suddenly, um, you're feeling snacky, um, because THC interacts with the
hunger part of the brain and also, uh, thc, um, makes food taste
better and smell better. And so you're more likely to,
uh, to smell or, you know, smell food being made in the other room
and start to salivate and you're like, oh my gosh, I'm actually
hungry. And so, uh, so those are the short
term effects of thc. So there are additional benefits
for specific ailments, but this, this list gives you a good understanding
of the most commonly used benefits of thc. And, and one or more of these are, are probably appropriate for you or the
patient that you're working with. So, so those are all the things that
THC will do for you now, today, as soon as you take it. So now, when taken over time from once a
day to twice a day or more for a few weeks, these daily benefits
start to stack up. Um, one of those reasons is a decrease
in chronic inflammation, right? If, if you're taking THC and in
that moment you're pushing back the inflammation a little bit, if
you continue to do that over time, you will be decreasing
your overall inflammation, not just decreasing it a little
bit for, for the next four hours. But if you decrease it now and then
you take THC again in four hours, and then you take it again in four
hours, and then you do that tomorrow, you can, um, decrease your, I guess, standard inflammation
that your body has, uh, which buys you some time to decrease
your discomfort while you are trying to figure out what is
causing your inflammation and, and decreasing those and
decrease those causes. Um, the second long term THC benefit
that I will tell you is probably the one that's the most important,
and that is, uh, apoptosis, um, THC kills cancer cells. And, um, it's very interesting to watch
it happen in a Petri dish. A a THC molecule come
up against a cancer cell and, and burst its side wall, um, which I swear has gotta be the word
where the term apoptosis comes from. And, um, and it kills the cancer cell.
And so, you know, if you just took, um, THC today, um, you know, it would
kill some cancer cells and that's great. And that's why a lot of people
use it as a, um, you know, some, a preventative for cancer. Because if
there are any cancer cells in your body, the THC will hopefully mop them
up while they're still small. But if you are taking THC every
day, you're, you're, you're, you're killing cancer cells now and then
you're killing more in four hours and then more in four hours,
and then more in four hours, and then you sleep and then
you do it again tomorrow. And so as you start to stack these
days, um, next to each other, um, suddenly you are decreasing the size of
tumors and other forms of cancer. And, and we have seen
significant, um, you know, both scientific and anecdotal evidence
that this works for a great many people on a variety of cancers.
And so, um, you know, uh, hopefully there will be another
episode like this where, um, where I'll be doing it solo and I
can, I can lay out the, um, you know, the entire application of, of the
cancer protocol. But, uh, for now, just understand that it causes apoptosis
and it's a great thing to take as a preventative. And finally, um, kind
of in the same category as the, as the appetite stimulant, that's
a short term effect long term, um, you can get weight gain
from the appetite. And, and so for people who have got like a
wasting disease or they're just losing weight long term because they're
depressed, well, you know, the, the, the munchies that you have today
and tomorrow and the third day, they start to add up and you
start putting weight on and, and hopefully start feeling
better. So, okay, so, um, now that we've kind of got an idea of
what the short term effects are and the longer term effects of
taking, uh, THC generally, um, let's start about talking about some
real specifics of, of the amounts, the, the milligrams that we're talking
about when taking thc. So, um, the first benchmark we
wanna look at is, um, a generally a sub
perceptible dosage of 2.5 milligrams. Now at 2.5 milligrams, um,
you really shouldn't feel it at all. It would be, it would be a surprise
if your patient felt it. Now, um, they may have anxiety about it, and so
they may think that they're feeling it, um, because placebo is a strong thing. Um, but generally at 2.3, unless, unless
somebody is exceptionally sensitive, they're not gonna feel it yet. So 2.5 is, is generally pretty safe for most
people, um, who are either, um, scared of the intoxication experience
or they've got control issues and they don't like to feel like they are
in any way, um, out of control. Or perhaps they had a really negative, um, THC high when they were younger, and
they just never wanna feel that again. And yet they need THC for some
reason. And so for these people, we start them off at, uh, 2.5,
uh, milligrams, which honestly, the most of us who use cannabis
regularly might scoff at 2.5. If you're taking 2.5 milligrams of
thc three to four times a day every three to four hours, and
you're doing that every day, you are going to see tremendous
results with your arthritis and, and other sorts of
inflammatory, um, issues, um, that just need to be addressed
every day in a small amount and not today in a large amount.
So, so don't rule out, um, 2.5 milligrams. Uh, it can
also be used to, you know, create appetite and,
uh, to a lesser extent, but it is true to, uh, give you a little bit of muscle
relaxation for just like physical comfort. So that, that would be our first, our
first benchmark is 2.5 milligrams, but, but five milligrams is where most
people start to feel it in some way. Um, it's often compared to one glass of
wine for most people, and this is, this, five milligrams is a, is the baseline
dose for most cannabis patients. Once patients get comfortable here, um, many to most we'll move up to
10 milligrams if they also like the feeling of it being a slight
euphoric, right? Because if, if the job that you need is
getting done at five milligrams, but if you take 10 milligrams
and it's also pleasurable, well, you know, a lot of people go to that
10 milligram mark pretty quickly, um, just because they're like, well, if my
medicine can make me feel good, like, okay, let's do that. Um, you'll
find that, uh, the majority of, uh, edibles that are sold in, um, medical
and licensed recreational shops, um, are 10 milligrams because
it, it just seems to be a, um, a, a uniform dose that can, um, help a wide range of people.
And so they'll give you,
you know, whatever it is, uh, 10 milligram gummies,
10 milligram cookies, um, 10 milligram gum drops, you know,
like whatever. Um, they'll, they'll, they'll likely give you
10 of those to a package. So there'll be 10 milligrams each, and then they'll be in a package of a
hundred milligrams that you can just take yourself. And so, um, at, at this, at this five to 10 area,
um, you're gonna need to, I mean, if you don't have an
experience with cannabis already, um, starting with 10 milligrams
might surprise you. And so, um, this is one of the reasons
why I recommended, um,
tincture earlier in the show, because if, if you have zero experience
with cannabis, um, starting with 10, um, milligrams, it might be great, but
then also it, it might not be for you. There's, there, there is a
lot of variability in folks, and even though 10 milligrams sounds
low to people who use cannabis all the time, um, to somebody who's particularly sensitive
and they've got a lot of CB one and CB two receptors, and so their body takes on a
lot of that THC really fast. They could have an
uncomfortable, um, you know, dysphoric experience and it happens
all the time. So whenever possible, you know, um, perhaps start with a tincture
and experiment at 2.5 and five and 10 and kind of find out
what your appropriate dosage is for what you're trying to take
care of. Um, and then, and then to, to understand what the really high end
of the numbers look like. Um, let's, let's, let's talk about
extreme examples. So, so, so if we're talking about like five
or 10 milligrams for most folks, if taken regularly, um, in contrast, it's common for cancer patients seeking
to beat the cancer to take as much as 750 milligrams of THC of
whole plant oil extract every day divided into three
servings of 250 milligrams. So, so we're comparing a potential
10 milligram THC serving to a 250 milligrams serving
three times a day. That's a whole bunch and actually a
devastating amount actually. And, um, you know, you don't start at
that, at that dosage. You know, part of the cannabis, uh, cancer
protocol is that you tight trade in. So you're starting with, you
know, lower amounts and then over, over the weeks you increase the amount
that you're taking with the hope that by the time you're taking 250
milligrams at a time, um, that you've got some amount of THC
and awareness of what it is to be high and, and, you know, awareness
of what it means to be, um, kind of uncontrollably high. Um, there are certainly people who can
handle 250 milligrams, um, you know, no sweat, but the vast majority of people
will be absolutely blown out at 250 milligrams to the
point that, you know, they could be questioning
their sanity, right? Which is, which is why you don't just take
250 milligrams without knowing what you're doing and in a cancer protocol, why you titrate your your way
in so you build up over time. It's also important to
understand that the, the, the maximum dose of THC that is
necessary for a patient is really their call. And even though somebody might not be
taking high levels of THC intentionally to cause apoptosis in cancer, there are other very unique patients
who take extraordinary amounts of, of thc. Um, you know, my, my my most significant example is my
buddy Nick Ryden, um, back in Michigan. He's a cannabis and dog breeder
who also has Lyme disease. And when I first visited
him at his home, uh, I was astonished to see him taking 400
or 500 milligrams of THC and cannabis oil three to four times a day. And I was
just astonished as, as he's just like, you know, squirting these
syringes into his mouth to, um, to help quell his seizures and
ease his pain. And, and, and I was, I was just astonished watching it,
and I was actually afraid for him, but he's like, oh man, I do this every
day. This is, this is all right. And, and so, you know, this is, this is where patients start to really
have to grow their own cannabis because being able to afford that much as a
patient on the open market is, is, um, very unrealistic. And so why I
always, um, you know, stand up for, for patients having the rights to grow
their own and be, um, self-sufficient. So the next thing we're gonna
talk about is, um, you know, once you're going over 10 milligrams, you're gonna learn how your particular
body responds, um, from thc, and you can move away from dosage
guidelines, um, like this one. Um, because all it's gonna take is,
is a couple weeks of you, uh, taking THC every day and, and you are
going to learn what works for you. And so guides like this
are to help you understand how to think about cannabis
dosing, but once you're doing it, you become the expert for your body
because everybody's body really is different. This is why I always
recommend that people keep a, uh, a dosing journal of their
cannabis use because, um, over time you might forget how much
you used to take for this or that, or, or you, you might wanna look back and
see how you try titrate it in. Um, also, if, if you're gonna bother to tell
your doctor about your THC use as, as part of your overall
health solution, um, doctors like really dig it if you can
show them that you're taking, that you're, you know, keeping a journal and
that you're tracking this stuff, um, cuz so many doctors are already very
suspicious of cannabis medicine, but if you can show that you're
doing it in a controlled air quotes responsible way, um, you know,
they might be more likely to, to, you know, play with you and,
and, and not give you, you know, a hard time about using it. So, um, there are two varieties of black swan
patients that we need to talk about before we end this, um, this
discussion of, of THC specifically. Um, the first one, um, we're gonna
talk about our rapid metabolizers. Um, there is a variety of human that just
metabolizes everything super fast. And, uh, I have worked with these patients
and they metabolize THC so fast and, and often mushrooms and Ls,
L S D and, um, you know, anything you give them, they, they metabolize it super
fast to get almost no effect. And, um, we have to know
that these folks exist. I, I worked with this one patient who, um, had no experience with cannabis prior,
and then they decided that they, um, you know, needed to take it for
their health. And so they started with, you know, the, you know, the 2.55 milligram 10 milligram
and like didn't feel anything, and so then moved up to 40
and didn't feel anything and, and they found that their, um, uh, efficacious dose was actually, um, 80 milligrams of THC at a time. And, and this patient was still like doing
stuff around the house and being productive and it's, it's, it's actually what they needed
to take care of their, um, their ailment and function
like a normal human. But, but if you told me that somebody who had
only been taking THC for two weeks was already at 80 milligrams, I would fear
for them, you know, that they, that, that they were taking so
much that, um, you know, if, if they took that 80 milligram amount
that they would have a very bad day. Um, and yet this, this patient just like worked titrated
themselves up over the course of four or five days, and now they sit
at 80 milligrams and you know, that kind of rapid
metabolizer is very rare, but if you are a caregiver, you know, it's also important that you know that
it exists. And if you are a patient, um, now you have keywords to, um, to search so that you can show
your caregivers that yes, you, you, you may require this much thc. Um, the second variety of black swan is that
it's estimated that about one in 10,000 patients are wildly sensitive
to thc. Um, the point where, you know, only a, a gram
or two, or excuse me, a milligram or two is, uh, going to give them a very bad experience.
And I've only seen this once. Um, uh, a patient, uh, reached out to me
during their very bad experience. They, they took a, um, a five milligram tincture
that they got at the, uh, licensed store and they
experienced dysphoria, hallucinations and, and like intense energy for 12
hours from such a small dose. And honestly, I wouldn't have
believed it if I hadn't first, if I hadn't seen it firsthand. And I was familiar with that
product and knew that, um, that analytics on it were,
were likely right and, and that that dose is so small and, and should have such an incredibly
small effect. But I, I saw it happen. And so, um, we do do need to be aware that on the
rare occasion you can give a very small dose to a patient and they
will have an outside resized response to it. And, um, they're
gonna need some support in, you know, just trying to stay calm and
feel okay until it wears off, like towards the end of
the day. So, um, you know, I hope for you that you don't come
across either rapid metabolizers or, or hypersensitive folks
to THC because, um, it, it's always a real surprise and,
and as a caregiver, um, you know, you feel so bad for 'em, you know,
because they're, they're, they're, they're trying to do their best with
cannabis medicine and now they're like blown out and they've had a
really bad experience and, um, and now they, they now they really hate
cannabis medicine. So, um, so I, I, I hope that, um, I hope that you aren't
one and I hope that you don't, you know, come across them in your work. All
right, so let's move on to CBD Now, you probably have got a pretty good
idea how to work with THC at this point, hopefully. So, so cbd, um,
which stands for cannabidiol, uh, it activates the CB
one and CB two receptors, but to a much lesser
extent than THC does. Um, it doesn't cause intoxication, but it's
is certainly psychoactive. You know, a lot of people say, oh, it's not
psychoactive, but, um, while it, it won't get you high like THC
will, um, it is definitely, certainly psychoactive in the sense that
it can change perceptions by bettering your mood. Um, how CBD exerts its therapeutic impact
on a molecular level is still being sorted out. Um, cannabidiol
is a pleo pleotropic drug, which I don't usually have much, much opportunity to say in that it
produces many effects through multiple molecular pathways. The scientific literature has identified
more than 65 molecular targets of C B D, and the study of these
pathways has always only just begun. So while we do talk about
C B D interacting somewhat with the CB one and CB two receptors, it isn't that they overdose
don't interact with receptors, they interact with a lot of things,
and we're just now trying to, you know, figure out what those, what
those other types of, of receptors, um, might be, what those might look like. CBD is a very active signaling molecule,
and it's one of the most useful, um, cannabinoids for the
endocannabinoid system. Um, because of this variety
of 65 plus targets. Um, it does a lot, uh, to support
the endocannabinoid system. It feels very much like a utility
player, like whatever's needed, you know, come, you know, fill in, you know, uh, phyto cannabinoid version of CBD
to replace endo cannabinoids. And so it's, um, it's definitely
a workhorse. Um, similar to thc, CBD has benefits now
and benefits later, uh, for certain THC is more
of a, help me today, cannabinoid and CBD is a bit more
of a help me tomorrow cannabinoid, because for most of its applications, it takes time to strengthen
the endocannabinoid system. But it's true that CBD two has
some today benefits. So, so let's, let's talk about short term and long
term benefits just like we did with thc. So, uh, shorter term
benefits of cbd. Number one, the most low hanging fruit, uh,
brain chemistry, mood, anxiety, and stress. Um, this is of, of all the
things that I tell people, you know, you need to give CBD some time to
do its job when it comes to mood, anxiety and stress. This is something
that it can help you, um, you know, like within an hour depending on dose
and your receptibility to it. Um, then the reason is, is because cannabidiol
stimulates the five h t one a serotonin receptor. And so you take it and it goes
and it activates it and, um, your mood, your brain chemistry
will start to even out. Um, as we talked at the top of the
show in the first set, the, the main goal of the endocannabinoid
system is to balance, um, the body's other systems. And that is what's what's
happening in this effect if, if your chemistry has swung one way or
another, causing you to be either be, you know, depressed or anxious, um, CBD will help bring you back to the
balance place where you can be your best. Um, it is also an antiemetic
and an anti nausea like THC is. And when you use them together, they
work together to be even more effective. And then C b D binds to, uh, they're
called Trip V one receptors, uh, T R P V one receptors, which
also function as ion channels. And so these trip V one s are
known to mediate pain, um, and inflammation and body temperature. But the main thing that people are
looking to it for is to mediate pain. So, um, CBD of course, is handling the experience of pain
very differently than THC does. And so when people put cannabis all in
one bucket on how it helps with pain, um, you know that they don't really
understand the medicine very well because, uh, thc, as we've already learned, it helps by being a natural
analgesic and decreasing the, um, the muscle contraction as well as,
uh, being a distraction, right? Well, C B D in its own way, um, it, uh, activates the trip V one, which
mediates the pain perception. So it kind of just like turns down
the volume of your experience of it. So when, again, when you have
CBD and THC together, um, they work really well at
decreasing pain today. So the longer term pen of benefits of CBD
are usually what people are going for. Very often the short term benefits,
people are looking to, uh, THC for help, and, and they
may have heard CBD helps, but, but realistically, c's, um, most effective role is to strengthen
the endocannabinoid system so it can do its job, right? And so the longer term benefits
of CBD would be number one, first and foremost to strengthen
the endocannabinoid system so it can do its job in rebalancing,
uh, the various body's systems. And the body can heal itself. It just needs some more
signaling molecules and cbd, because it targets these, um, 65, uh, different receptors. Um, it has a little bit of help
for all the different systems. And so it is a great thing to supplement
yourself with every day to strengthen your body's ability to
take care of itself. CBD also exerts an
anti-cancer effect as well, and I won't get too much into
the mechanics of it, but, but what it does is it, it, it has an
anti-proliferative effect, which means, um, it slows down cancer's
ability to replicate itself. And, uh, again, if you're taking
it every day over time, uh, you would have, uh, the
CBD slowing the, uh, increase in number of cancer cells, and then you'd also have THC
coming in and bursting those cells. So they're a very good
team in this regard. Um, also another great thing is that, um, CBD tends to kick off the
body's housekeeping mechanisms. And so it is helping take
care of, of things that if, if allowed to go neglected
over a long term, um, can get especially worse.
So for example, um, uh, when you take C B D, um, it activates the P P R gamma, which degrades the amyloid
beta plaque in the brain. And when this plaque builds up, it is linked to the development
of Alzheimer's disease. And so when you are taking C B D as a prophylactic, like daily, just so
things don't get bad or worse for you, you are actually sting off a, a certain amount of potential
of Alzheimer's in the future. We've also seen patients that have, like, they're starting to have dementia and
then they start with a pretty heavy daily use of C B D and their
dementia tends to calm down. Um, both probably because of this, uh, p P ar gamma activation. Um, but also because C B D causes
neurogenesis the creation of new brain cells, new neurons,
especially the ones that are, uh, dopamine excreting and these
dopamine excreting neurons, um, help stave off, um,
things like Parkinson's. And so it really is helpful
to use C B D on a daily basis. Um, you know, probably for everybody, since we know that just about everybody
is suffering from endocannabinoid deficiency, but especially
as you're getting older and your body isn't working
as well as it used to, and you're starting to forget things and
you're starting to be more aware of a potential dementia or
Parkinson's in your future, like, like you don't wanna go too
long without supplementing your endocannabinoid system so it can do
the business of keeping you healthy. Now, if you really wanna
dive into understanding cbd, the only place I recommend is project
c b.org that I mentioned at the top of this show. Um, founder
Martin Lee has put together a, an exceptional cannabis
resource for patients, and it's the only online
source that I fully trust. So the articles are
written in layman's terms, and then they also provi provide direct
links to the original scientific papers. So, so don't forget project
c d, it is a, it is a great, and as far as I'm concerned,
the only place to go online. So there's a great deal of confusion
and debate about the proper dosing of C B D. So when using whole plant, we can offer c b milligram suggestions, but the other cannabinoids in the
resin will always play an uncontrolled role because we don't know how C
B D might interact with the canna flavin that is also in the resin and
what they might be doing synergistically together. So CBD in a whole resin
goes further than just a CBD isolate because it's got
its partners in the resin, all the other components of
the resin, they're with it. And so because of that CBD whole resin
will almost, nearly always give you a, um, a better efficacious experience than
just isolate alone. But again, if you don't have access to CBD
resin or you can't afford it at the amount that you need, uh, by
all means give a high quality cbd, isolate a try and see if that
will help you. All right. So with that, let's talk to,
let's talk some specific numbers. So looking back to 2015, when I was
first recommending CBD to patients, you know, doctors willing to take a position
at all said that about 10 milligrams per day of whole plant cbd, um, was good for, as a supplement that would support
a healthy person to stay healthy. And I think that the actuality
for healthy people is probably twice that. So 10 milligrams twice a day, once in the morning and once again
after lunch, um, not in the evening. Cuz about 20% of people find
CBD stimulating and, um, not stimulating in a way of like coffee
or caffeine or anything like that. It more stimulating where,
um, when people take this cbd, suddenly their body wants to
do that housekeeping stuff
like removing the plaque on the synapses in the brain and,
uh, cleaning up the mucus off the, the, the, um, Celia in the gut. And so you don't really want
to kick all that stuff off, um, as you are, um, you know, trying
to, trying to go to sleep. And so, but you know, that's only
about 20% of patients. But I don't recommend that
people take, uh, C B d uh, in the evening unless they've
already had a trial, right? And you don't wanna do your trial like
on a work night or a school night or something like that. Try it on
a, try it on a Saturday. So, so that you make sure that you're
not reactive to C B D and, uh, making it more difficult to sleep. So
as soon as you have something wrong, that number of 10 milligrams
twice a day will jump up. And if you're actively working on an
issue like arthritic inflammation, migraines, IBS, or
something like that, um, you immediately are gonna wanna jump up
to more like 20 to 40 milligrams twice a day. Um, and, and that will work on your endocannabinoid
system at a rate that you're likely to see something even maybe within a week. But I always recommend a full
month of daily C B D as a trial because it, it does take your body
some time to rebuild the
endocannabinoid system enough to probably meet your goals. And
we don't know how many, uh, uh, c b receptors that you have in your
body. You might have more or less. So it may take longer for your body
to get the reaction to the daily supplementation of CBD that you're
looking for. And, you know, a month is, it's not too long, but it
is enough, right? If, if, if you've taken it for a month and you're
taking enough every day and you're not really seeing results at
the end of the month, well, you might as well put
your money elsewhere. Now, if you're dealing with something big
and chronic like rheumatoid arthritis or lupus, or multiple sclerosis
or just wicked joint pain, the right answer for most people is
probably to take as much as you can afford. And this is so frustrating to
patients when I'm talking to them because, um, you know, if they've got something serious and
whole plant is expensive and sometimes hard to find, um, they're just all
like, well, how much do I need? And, and I'm all like, well, you know,
it's expensive. How much can you afford? And which is a very frustrating
answer, and I, and I understand that. So I try to give them an idea of how
many milligrams of CBD they want, and then they start doing the math and
they're like, oh man, you know, that's, that's half of a cbd, uh, syringe, and I need that, you know, twice a day.
So you're going through like one a day. And depending where
you are in the country, those CBD syringes can be anywhere
between 30 and 80 bucks each. And, um, it's not like the old
days where, um, you know, in, in many states medical systems when
you were buying from, from the grower, um, there was always a discount to
people who had, uh, chronic illnesses, especially people who,
um, were fighting cancer. Because by the time you're fighting
cancer, most people are broke when they, when they find their way
to cannabis. And so, um, it's very challenging to
recommend CBD for people who who need a lot of it. And, you know,
perhaps for some of those people, a good solution will be
to purchase C B D, um, whole plant oil in a syringe, and
then maybe even spike it with, with isolate to get more
bang for your buck. Now, um, I have a chronic disease and I
take 80 milligrams twice a day, but I grow my own and I make my own oil. So my costs are much lower than at
a licensed store. And this, again, is why I'm a big proponent of
cannabis patient self-sufficiency. And I really hope that our society
continues to increase our support of that. So before I go on to the
Black Swan patients around cbd, I wanna kind of like wrap up the numbers
of dosing that I was suggesting into a little nicer package because,
um, I can imagine that it, it might feel a little, a
little vague at this point, especially when I've all like, take
as much as you can afford, right? So, so we essentially have got
three different levels of, of dosing and, and to find out where your dosing
may need to be for your particular ailment, again, I send
you back to, um, the, uh, project CBD site because
on project cbd.org, you can find the actual studies and you
can find out how much CBD they're giving the patients, what
their results were like, and if they were using a whole plant
or an isolate, uh, preparation. And because at this point
you understand that, um, the whole plant tends to be more, more
effective and then isolate, you can, you can start to kind of gauge
where your particular needs are, uh, for where you wanna
start your, your dosing, and then you can start
making your changes after, after you see or don't
see, um, effects. So those, those three levels are, um, if you're, if you're generally healthy and
you wanna stay that way, um, shoot for 10 milligrams of
CBD twice a day as a minimum, if you can afford or get your
hands on more, well, that's, that's all the better. But, um, but the, the doctors that I have talked to
and interviewed say that, you know, if you're not actually actively
trying to fix something, taking 10 milligrams twice a day
for 20 milligrams a day is a, is a great place to go.
Um, the next level up are, if there is something actively you're
trying to work on, like you're, um, like migraines, like ibs, like arthritic inflammation
in the arms or, or in, or, or in your knees or whatever, and that,
that you're really talking about, um, like 40 milligrams twice a day
at that middle, middle place. And then of course, there's this
high end where, you know, if, if they're using 200
milligram doses in trials, um, not a lot of people can afford
200 milligrams of whole plant CBD or maybe even isolate cbd.
And so you just, you know, you take as much as you can and, and perhaps you can find yourself
a syringe of c whole plant and then spike it with some isolate
and get creative. And so, um, while that seems a bit on the vague
side, there's a lot of different things. There's dozens of different ailments
that CBD can help with. And, um, you know, this isn't a
show just about dosing cbd. I wanna teach you how to
think about how to dose cbd, and then you can continue with a
little bit more of your own research. And this will provide a, a context for you to put that new
information in as you are, um, designing your own protocol.
All right, so OneNote on, uh, black swan patients around cbd. So I have worked with one immune
compromised patient who also had rheumatoid arthritis, and we become delirious and
experience missing time after simply ingesting 10 milligrams of
C in a whole plant cannabis oil. And, you know, and it was really hard to
believe it unless I had seen it. And I saw it a few times. And we know that it wasn't
very high in THC in the oil because it was hemp
extracted and lab tested. And so we're certain that the THC
component was under one milligram, and yet something in this
patient was definitely activated. And on more than one occasion, because the patient had a long
history of using this same oil, suddenly when they took
the oil at this low amount of just 10 milligrams, they were, they were losing entire afternoons and, and were kind of delirious and tired
and had to sleep the rest of the day. We still don't know what that is.
And when I talked to, you know, canna apathic scientists, um, they, they're skeptical and they
don't wanna believe me, but I've been doing this a long time now
and I know this stuff to rule out and so I see it. So, um, I don't really tell you this to caution
you against CBD cuz CBD is so safe. Um, but you know, this is an extraordinarily rare thing
and I bring it up in case you are a caregiver and you come across
a patient like this. Um, know, just know that it's possible humans
are incredibly varied and knowing that something is possible, even if rare can help us guide
patients should they have this sort of rare reaction. So before
we close this CBD section, it's worthwhile to
mention that C B D A, um, which is the acid and raw form
unheated form of CBD that is present in the cannabis plant, also has a strong affinity for
the five HT one A receptor, even more so than cbd. And preclinical studies indicate
that CBD A is also a potent antiemetic nausea
stronger than CBD or thc, which also have the antinausea properties. And the reason why I dropped this
in here is just to kind of, uh, ignite the idea in you
that while most of the preparations of medicine that
we have are not the acid forms, so most of the time what is
available to us is C B D, not C B C B D A. And by
the time we take thc, it's THC and not thc A we need to
remember that the acid forms that have not be been decarboxylated or heated, um, they have their own, uh, sets of ways that they help the
endocannabinoid system. And, and don't be shy about taking your
cannabinoids raw right from the plant. Um, say for example, by making hash
and just eating it instead of, uh, using some kind of preparation that,
uh, you have to heat it either by, uh, making an extracted cannabis oil,
which you have to heat to remove the, um, the ethanol, um, or, or, you know, traditionally smoking thc
where the burning of it is the decarboxylation process. So it's just in, it's just valuable to understand that
these acid forms of these cannabinoids often have entirely different useful
properties than their non-acid forms. Okay, so the third one we're
gonna cover, um, in this set is, is cbg. And, and we're
gonna cover this, um, in a shorter amount of time than THC
and C B D cuz I would say that the vast majority of people who are here are
looking for dosing recommendations for THC and cbd, cuz those are the ones that have been
studied the most and the ones that we can get our hands on the most. But CBG is
now becoming increasingly available, uh, ever since some C B G dominant, um, cannabis plants, um, found their
way into the market, you know, about five years ago now.
So, so now there are, uh, many hemp farms that are growing
cbg, CBG dominant plants. And so CBG is now available
in isolate form and, um, and as a whole plant resin
too. Uh, I must admit, I don't see CBG resin
available just anywhere. And, um, you know, I have to grow my own plants and make
it myself if I want it because, um, it's not, it's not available in
the licensed recreational, um, system where I live. So one of the newest cannabinoids
to get attention and one with very specific NU uses is CBG cannabigerol. So I'm going to delineate two
specific uses for CBG and then, and then give you the
dosing regimen for it. So we found when we did our
research here on Vaon Island three years ago when we gave CBG to
a round of patients and then did a questionnaire afterwards
that, um, the number one, um, uh, the number one thing
that people responded to was
that it helped neuropathic pain. So that's pain from some kind of
nervous system damage or dysregulation like, like a stabbing pain that seems
without cause or cold or numb fingers or limbs, that, that feeling
of pins and needles, for example. Um, um, and, and especially on
your, um, um, periphery, right? The external parts of your
body. And so when people, uh, take cbg, um, it
decreases that experience. And, um, it is true. We don't, we don't
know exactly know why yet, but, uh, we do know that it happens
and it, and it happens, um, pretty consistently across
the board. Some of the, some of the things that cannabis help
with, we have to very much say, oh, your mileage may vary. But, um, these two attributes in CBG seems to
be pretty reliable across the board. And one of the great things about CBG is
that, um, it doesn't have intoxication. So it, it, it, unless you are, are taking a CBG from a
plant that it's married to THC in the preparation, like, like you don't grow a CBG
hemp plant. Instead, you, you grow a one to one plant
that's one part CBG and one part thc. So long as you're, you're not
intentionally adding the THC component, CBG on its own won't get you high, which makes it very reliable
for lots of people who have pain, but they don't want to
feel any level of intoxication. And CBG is incredibly reliable for this. The second great use for CBG
is, uh, actually anxiety. Um, I was really surprised when we got back
the questionnaires and, and there were, there were multiple different flavors
of anxiety that people found great help with. So, um, the first
one was social anxiety. People said that it kind of like calmed
them down and it allowed them to be social and interact with other people.
Uh, we also heard from people that, um, it, uh, softened performance
anxiety, so public speaking or, um, at the beginning of covid
when everyone was getting
on Zoom meetings for the first time, you know, zoom meetings
are very socially awkward situations, and a lot of people found
it very uncomfortable to be
doing these Zoom meetings. And CBG helped people like cool out
so that they could, um, tolerate the, the awkwardness stay calm and
engaged and, and be productive, uh, in their Zoom meetings. And then
the third one was a real surprise. Many patients would explain
it to me by, by putting their, their hands on their hips and, and thrusting their chest out like a
superhero would. And, and they'd say like, it gives me the confidence of a superhero.
And after I heard that enough times, I, I really had to start like listening
and thinking about it because people really seem to get an increase
of confidence from it. Like, and how they described
it is, I feel like, um, I feel like I have the resources to
get what I need to get done today versus, you know, if you wake up with
rumination and you're like, oh my gosh, I just don't, I just don't have what
it takes to get through the day, that can really just like
hold you back your entire day. But if you start your day with a little
CBG and suddenly you're all like, okay, I can handle this, let's go. And, um, it showed up very significantly in
the questionnaires that we got back. But then also in the three years
since then, um, uh, I just, I just see it in patience
all the time when they, when they tell me that they have sourced
it and they're using it and they're loving it and they never wanna
not have it again. And so, um, CBG cannabigerol can be relied on for, um, as a really reliable anti-anxiety
with no intoxication. Okay, so now the specific numbers
and milligrams that, that we're seeing people
have success with, um, uh, 10 milligrams of CBG every
three hours does a great job for both. So if you want to
use it as a pain reliever, 10 milligrams of CBG
every three hours does, does usually has fantastic results. Um, if you have got a very
high background anxiety, you might need to take CBG
multiple times throughout the day, but really for most folks, they'll take it in the morning
and it kind of sets them on the, on an anti-anxiety path for the day, and they just seem to be like
okay with that one dose. Now, if they have like a stress
event in the afternoon, um, many people will take it
again. But really, um, unless you already have chronic anxiety, if you just like have a bit of anxiety
or if you have like morning rumination that you need to get rid of, you may get away with just taking 10
milligrams of whole plant CBG just once in the morning and good for the
rest of the day. But, you know, if your anxiety continues throughout
the day, you can certainly take it, um, as needed because taking more, um,
has got no negative impact. Now, 20 milligrams makes it happen even
faster and with a bit more, um, spun. So, uh, let's say that, um, you know, generally you take 10 milligrams just
because you've got a high background anxiety, but, um, today you need
to give a presentation, right? And so your, your, your anxiety
is going to be especially peaked. Well then go ahead and take 20 milligrams
and, and don't monkey around with it, right? Um, and those are, those are great
low numbers, right? You know, if you, if you think back to the thc we were
talking, you know, um, you know, 10, you know, five or 10, but then the
c we were talking 80 and 200, well, this is back down to, uh, THC levels more like 10
or 20 milligrams and, uh, makes it much more affordable
if you can find it, because the CBG that is available to
you, um, just lasts a whole lot longer. Okay? So, uh, to wrap up this
second set, we looked at, um, the, the, you know, how to think about dosing
for THC and for C B D and for cbg. And granted there are a lot of
other cannabinoids out there, but, um, between the lack of
availability in most places and the lack of the research about
what is an effective dose, um, I don't wanna give you information
that is not solidified yet. And, and so since these are the three
cannabinoids that most people, um, have easier access to, this is, this is
what we are going to talk about today. And as new cannabinoids become
more available in the future, like for example, cbn, we're gonna
be seeing a lot more of CBN soon. Um, you know, when that
comes, you will have, um, you will have the proper understanding
and context to look at the studies that are coming out and being published
on project cbd.org and learning how to add that to your own particular
health protocol with cannabis medicine. All right, so, um, uh, we're gonna take our short break and
when we come back with set three, we're gonna talk about,
um, some use cases, um, uh, like arthritis and leg and joint
pain and neuropathy. And, and, and we'll just talk about, um, thinking
through some of these use cases, um, to make sure that you really understand
how to think through doing your dosing. Because like I've said, everybody's
dosing in the end is unique. We, we can give you these guides to
get you started, but in the end, you will be divide, devising your own protocol as you get to
understand how cannabis medicine works and how it works with
your own body. So, uh, we're going to take a short
break and be right back. You are listening to the hundredth episode
of Shaping Fire. And I am Shago Lo. Without these advertisers
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click on the link in the newsletter. Welcome back, you are listening
to Shaping Fire, episode 100, and I am your host, Shang. Go Lo.
So here we are in the third set, the big wrap up. So during the first set, we learned about how our endocannabinoid
system functions and considered some of the different ways to take cannabis
medicine into your body based on what, uh, is gonna be best to suit, uh, the
ailment that you are working with. During the second set, we
talked about very specific, um, dosing strategies and how to
consider dosing protocols, um, for the most popular three
cannabinoids that people, um, look to supplement with
thc, C, B, D and cbg. And here in set three, which hopefully
will be, uh, shorter than the first two, um, we're gonna talk about,
um, 1, 2, 3, 4, 5, 6 specific, um, um, issues that people come to me
asking for dosing strategies for. And we'll go over those
kind of swiftly since, since you've heard most of the analysis
already earlier in the show. Um, I'm just gonna tie them together,
um, which should, you know, kind of give you a roadmap to how you
can think about them yourself. So, alright, let's get right to it. So the first one we're gonna talk
about is kind of this bucket of issues, which is arthritis, leg and
joint pain and neuropathy. Um, the thing that these all
have in common is that, uh, it is an ongoing chronic
discomfort or pain, um, most likely caused by inflammation. And so even though it, it manifests
differently in these different issues, um, they, they really do have, uh, a lot of similarity in how
we're gonna treat them. And so if somebody came to me with one
of three these, this is what I would say, um, first of all, I would recommend, uh, 2.5 to five milligrams of THC
if they are intolerant of thc or are especially
concerned about, you know, feeling out of control or high
in any way. Um, and then if they, I would also tell them that once
they built up a comfort with, uh, taking thc, or if they already take
thc, perhaps they are a, you know, a recreational toker or something, then go ahead and start with
five to 10 milligrams. You know, if they are THC tolerance, um, you know, if you build up a
tolerance from daily use, this number can go as high as
a hundred milligrams or more. As we've already talked about, these patients could probably benefit
from a tolerance break from the thc. And I understand that some patients
cannot live a day without thc, so I'm not being cocky about it or
ableist. What I'm trying to say is, if you can work it out for a day
or two or more to not take THC to bring your tolerance down from needing
to take a hundred milligrams a day, it would probably be both physically
and financially of benefit to you. And the last thing I would say
here is to consider a topical, um, with arthritis and leg and joint
pain and often neuropathy, um, you can actually use a THC based
topical localized and targeted to where the discomfort's coming from. And then that way you are
taking cannabinoids orally, which will help with, uh,
systemic anti-inflammation. But also when you place the topical
locally, you're getting, you know, you're doubling down on making sure
that you're applying cannabinoids in the proper area. If you are making your own tinctures
and you are aware that topicals are expensive, I encourage you to just take some
of your tincture and, you know, a ramn like they serve you
ketchup in at the restaurant. Go ahead and put some kind of a hand
lotion or a massage lotion or like luberderm or something in one of
those little, uh, ketchup rams. And then put just a little bit of your
tincture in it and swirled around with, with your finger. And now you
have made instant topical. Um, it's what I used in the early days, um,
before I learned how to make topicals. And it works absolutely fantastic. So you can consider that and save a lot
of money on the kind of prices that they charge for topicals at the
licensed stores. All right, so that's a quick run through of arthritis
leg and joint pain and neuropathy. Let's talk about cancer symptom relief. So we're not talking about the full
fight cancer protocol here and, and hopefully we'll do
this again sometime and, and I'll talk about the cancer
fighting protocol in detail. What we're talking about here is, um, for patients who have
got cancer and are, um, either simply just suffering from
the cancer and they, they're, that's all they're doing. Um, so they're looking for comfort or more
commonly they've chosen to go the route of, uh, some variety of, uh, chemotherapy. And so they are dealing with
the symptoms from the chemo, um, stacked on top of the discomfort
and, um, from the cancer, uh, experience itself.
So for these people, the first thing I would
recommend is, um, uh, thc. And that's gonna help
them in so many ways. The first thing it's gonna do is just
make them them a little more comfortable in their body. By the time
cancer has gotten advanced, and especially if you are, um,
taking any kind of chemo, your, your human meat suit is just not
feeling like your ally anymore. Um, you've got aches and pains and things
aren't working properly and fluids aren't moving properly, and it's just all
around lack of comfort. But, um, taking five to 10 milligrams of
THC based tincture is going to put you in a place where you feel a
little more comfortable in your body. Your muscles are a little more relent
relaxed instead of just being clenched. And, um, and you're a little
distracted from the THC too. And you know, you haven't really
changed the status of your body. Your body is still incredibly
uncomfortable and sick. However, you can get a little bit of respite
just from the THC and the relaxation and the, and the easing of your human. Also that THC is very likely to
give you an appetite as well. And as we know, um, cancer
patients, especially in chemo, tend to lose their appetite. And we
really don't want you thinning down. At the same time, we wanna try to
help you keep weight on so that, um, you know, you don't slip into some
kind of a, a wasting, um, cycle. Uh, cuz that's, that's not
usually a good sign. Um, if you have access to
thc, a that's the, um, that's THC that has not been
heated or decar vaccinated THC is actually really effective in, um, cancer patients for helping
rebuild appetite as well. Um, just in case for you, THC is not appetite forming,
uh, try the acid form. Um, we get a lot of good results
with that here on the island, um, ever since we started talking about
it. So that's been, uh, real positive. And so, and the last thing for cancer symptom
relief is to just simply take as much whole plant C b D oil as as you can
afford, as we discussed earlier, because your body's endocannabinoid
system is probably a wreck from all of the pharmaceuticals
and especially if you are taking chemo and your body's natural
balancing system is, has been totally traumatized. And so you're not properly
making signaling molecules and, and endocannabinoids and you could
really benefit from dumping as much c b D into your body as you can
likely afford. So, um, you know, I I guess I should put a a top
on it. I wouldn't put, you know, more than 400 milligrams of
whole plant into, um, you know, a day. You, you probably, your body
probably couldn't process more than that. And I actually don't have an opinion on,
uh, how much isolate is a maximum. Um, and, and especially for cancer, I would really recommend that you
use a whole plant preparation so that you're getting all the secondary,
uh, novel cannabinoids and, um, the other synergistic components that
we're not entirely certain how they help out yet, like canif, flavin
and the others. For example, let's talk about migraines. So migraines,
um, they're kind of low hanging fruit, um, either works or it doesn't, but what the dosage is is pretty
basic and it's 20 milligrams of whole plant CBD two times a day minimum. So you can take more if you'd
like, of course. Um, but, uh, 20 milligrams two times a day, uh,
seems to work pretty well for folks. Once people realize whether or not
they are of the 20% of people who are kept awake at night by CBD
because of it activating the body's housekeeping, if
you're not one of those 20%, go ahead and take it in
the evening too, which, uh, hopefully will act as a prophylactic so
you don't wake up in the morning with a migraine. But be aware that if you
are one of the 20% of people that CBD keeps up at night, um, you wanna avoid that cuz that probably
will increase your likelihood of actually waking up with a migraine. I
also would have you consider, uh, a small amount of THC for muscle
relaxation because we know that not only does a relaxation
of the muscle sets help decrease the likelihood of
migraines, but if you are, uh, pretty severe migraine patient, your body's fear of having another
migraine and going through that, that cycle of pain and discomfort
itself can cause the body to, um, constrict, which in and of itself can cause
migraines and, and it just feels bad. So if you're not resistant
to, uh, trying thc, um, taking five milligrams of
a THC tincture along with the 20 milligrams of C B D, um, uh, will likely help you either
move out of a migraine or even better, uh, be a preventative. I would
also consider, uh, have you consider, um, microdosing psilocybin mushrooms at uh, one milligrams, um, taken
20 days a month. Um, if you'd like to learn more about working
with your migraine using psilocybin mushrooms, I encourage you to listen to
shaping fire episodes 67 with Dr. Russo, where we talk all about treating
migraines with cannabis and, um, soy mushrooms. It's a good one. The next
one we're gonna talk about is insomnia. Insomnia is incredibly common, um, for me to hear about because so many
people have got it for different reasons and it is actually pretty easy
to treat with, um, with cannabis. The first question I
always ask people though, when they tell me that they have insomnia
is not one that they generally like, and that question is always, um, do you drink coffee in the morning
because that is the first thing to go. The halflife of the drug we
call caffeine is 14 hours. So by the time you are drinking
tomorrow morning's coffee, you are still on yesterday's caffeine
that you took in the morning. And if this is continuing every day, you're never not on caffeine, which means that when you're
trying to go to sleep at night, you are always fighting against a
stimulant that you took not only that morning, but yesterday morning as well. And so that would be the first
place is to stop drinking caffeine. Um, second, I would ask them what they think their
source of their insomnia or what, what's the flavor? Um, insomnia
tends to fall into two categories. One being some sort of discomfort or pain, and then the other sort being some
sort of anxiety or rumination. And then I would suggest for
them solutions for the pain or the anxiety rumination. Um, but oddly they do tend to be both
the same cannabis prescription, which is five to 10 milligrams
of an indica tincture made using purple
flowering cannabis plants. Now I know that the terms sativa
and indica are antiquated, but people are still using them and
they can be helpful when going to, you know, a licensed store and
talking with a bud tenderer. But what we're looking
for are, uh, a tinctures, preferably made from plants
from the, you know, Afghanistan, Pakistan region, um, that are purple
because these plants, um, are, uh, heavily narcotic and lethargic
and that's what we wanna do, right? We want to cause drowsiness and
we want to cause muscle relaxation and we want to slow you down and make
you feel a little dreamy and then put you to sleep. Also, these plants, these
purple flowering cannabis plants, um, they're usually packed with the turpen, the terpenes mirroring and lulu, which also help you feel drowsy
and have you go to sleep. Um, specifically if the insomnia is
caused by anxiety and rumination, um, it would be really great, uh, to add
some CBG tincture to that as well. And if the person that you're
working with or yourself, um, is THC intolerant either on principle
or, or they're sensitive to it, um, you can just give them cbg um, CBG helps with both pain
and anxiety rumination. Um, so taking between 10 milligrams
and 20 milligrams of CBG for insomnia is very effective
for folks, especially if, um, they are very much not
interested in taking THC depression. Depression would be 20
milligrams two times a day of CBD where you're taking that because your
goal is to build up the endocannabinoid system and to help regulate
the brain chemistry. Um, this is something that you
wanna do long term, right? CBD is not something that you're just
gonna take Monday and then Thursday and then Sunday. No, no, no, you want to
take CBD every day because the benefits, the primary benefits come from building
up your endocannabinoid system and making it burley so it can do its
job regulating your body's systems. So that would be, um, 20
milligrams two times a day, three times if you can take it
in the evening, uh, of C B D. And also to put yourself in a good mood
and make things a little more tolerable while you're trying to
change yourself systemically. Go ahead and try to get your hands
on some CBG tincture or oil as well, and take 10 milligrams of that twice a
day in the morning and then after lunch. Um, that cbg my goodness, is it an effective anti-anxiety and it
just makes things feel a little better and the confidence that it
brings really helps even out the depression vibes of hopelessness. And then I would also recommend
microdosing, psilocybin,
microdosing psilocybin, um, really helps improve your neural
network and pull you out of a funk. Um, there's lots of research
on it to support it, and I encourage you to check out the, um, the microdose psilocybin
episodes on Shaping Fire. And the last one we're gonna talk about
here is neuro divergent support. Um, more and more people, especially during quarantine
when our lives got less thrilling and we were creating less
dopamine from having relatively boring quarantined lives. Um, a lot of people realized that they
have some flavor of neuro divergence. And while you figure that out, um, by doing your reading and
checking out the, uh, neuro, neuro divergent community on TikTok,
I also recommend, um, these, um, as potential things to help you get
through as you figure out the best combination for you. Uh,
40 milligrams of cbd, whole plant oil two times a day. Um, this is of course because we wanna build
up that endocannabinoid system and we wanna give our brain as many signaling
molecules as it can to do its job because neuro divergent brains, they are running hotter and faster than
other people's brains and they need intentional support. Um,
you're not driving a, you know, a regular car like everybody else. You're driving a Formula One and Formula
One cars. They need specialty tires, specialty oils, specialty
fluids, and so do you, my friend. Um, and I was also helpful to, you know,
keep things in a good perspective by, um, supplementing with CBG 10
milligrams two times a day. Um, and, and the reason is just simply, it's hard
out there for neuro divergent folks. This world was not designed
for the neuro divergent brain, and that can get incredibly frustrating.
And so taking some cbg giving you that, that confidence and a feeling that
you've got the resources to make it work, it can really make your days more
tolerable. Um, I'd also recommend, uh, 200 milligrams of L theanine. Now,
this is not a cannabis, uh, product, that's for sure. Um, but I know that neuro divergent
folks who run hot and anxious, um, find that L theanine,
200 milligrams of it, um, really evens out the
spiky parts of the day, the days that where you get
overstimulated and or harshed out from, uh, from, you know,
feeling over sensory inputted. Um, altheine does a really
great job taking out this, the scratchiness of your day. And if you
happen to be a person that's into thc, well, you know, having some THC tincture just to make
you too feel more comfortable in your body, that can o often feel strange to
you. Um, feel free to add, you know, five to 10 milligrams
of thc, um, as you wish. And good luck. So these, these, uh, these six areas that I just, you know, swiftly went through how I
would think through dosing suggestions, I, I did this
not because, you know, I can't go through everyth all the issues
that everybody has, but the idea is, I I wanted to give you a couple pictures, a couple examples of how you can
stack different, uh, cannabis, different cannabinoids along
with different antigens like psilocybin mushrooms, um, along
with occasional, you know, herbal supplements like Altheine and some
common sense like perhaps don't drink coffee if you're having
somnia. Um, so that you can, you know, figure out a stack for
yourself that meets your needs. Um, you don't have to do it the way other
people do. Individualized medicine is, is a thing and your body is
unique. And so, um, keep a journal, figure out what works for you and, and don't let your family or
doctors push you around. Um, I am a strong advocate of patients rights
as, as everybody knows, especially, um, uh, cannabis patient
self-sufficiency. So, um, it's your body take notes and,
and learn what's best for you. And I guess that's a wrap. Um,
if you are still with us, uh, thank you so much for listening
to this entire episode. Um, it is the longest shaping
fire episode that, um, I have published and I wanted to
get this all in one document, right? I have been thinking about this show and, and working on notes for
it for a long time now. And if you know you have found the
time to listen to it for yourself, um, I congratulate you. And if you are listening to this because
you were a caregiver or someone you love uses cannabis medicine, well I
really appreciate you too because, um, cannabis patients need all the help
and support and love that we can get. So, um, if you would
like to learn more, uh, please peruse the first hundred
episodes of the Shaping Fire podcast and subscribe to the show in
your favorite podcast app. There are so many great episodes for, uh, patients about patient health and for
how to cultivate your own cannabis in a healthy and organic regenerative way.
Um, who knows if you're a patient, maybe growing will be your new hobby. I also recommend that you check out
the Shaping Fire YouTube channel, where there are nearly 200
videos of speakers, um, from all sorts of different conventions
and such that I have attended over the years. And, um, I've just always
posted the videos there. Um, so you can find those, um, uh,
topics ranging from cannabis to, uh, mushrooms to IBO gain, all sorts
of different videos there on YouTube, just, uh, search YouTube Shaping Fire. So thanks for being here for
episode 100 of Shaping Fire and I am your host SHEO Lo. You can find more episodes of the
Shaping Fire Podcast and subscribe to the show@shapingfire.com and wherever you
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Fire. I've been your host, Chango Lo.